Universität zu Köln

El Beyrouti, Hazem ORCID: 0000-0001-6070-9490, Lescan, Mario, Doemland, Marco, Mustafi, Migdat, Jungmann, Florian, Jorg, Tobias, Halloum, Nancy and Dorweiler, Bernhard (2020). Early results of a low-profile stent-graft for thoracic endovascular aortic repair. PLoS One, 15 (11). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1932-6203

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Abstract

Purpose To assess outcomes of a low-profile thoracic stent-graft in the treatment of thoracic aortic pathologies. Methods A retrospective analysis of all consecutive patients with aortic thoracic pathologies treated with the RelayPro device in two university hospitals between October 2018 and July 2019. Results 23 patients (65% men; mean age 63.4 +/- 15 years) were treated. Pathologies included aortic dissections (n = 10), 5 residual type A (22%) and 5 type B (22%), 6 degenerative aortic aneurysms (26%), 4 penetrating aortic ulcers (17%), and aortic erosion, intramural hematoma and aortic rupture (n = 1 and 4% in each case). Two cases (9%) were emergent and two urgent. Proximal landing was achieved in zones 0 (4%), 1 (4%), 2 (43%), and 3 (26%). Five grafts were frozen elephant trunk extensions. Technical success was 100% with accurate device deployment in the intended landing zone of the aortic arch in all 23 patients and with no Ia/III endoleaks and three (13%) type II endoleaks. Apposition was adequate in 96%. Two patients had post-implantation syndromes (one fever, one leukocytosis). Mean follow-up was 11.6 +/- 3.7 months (range, 2-16) with no other complications, secondary interventions or conversions to open surgery. There was no 30-day mortality and no aortic-related mortality; all-cause mortality was 4% during follow-up. Conclusion A 3-4 French reduced profile in the current generation of stent-grafts facilitates TEVAR particularly in patients with smaller vessels access. Early safety and effectiveness outcomes are favorable, even in endpoints such as deployment accuracy and apposition which may be surrogates for longer-term clinical success and durability.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code El Beyrouti, Hazem UNSPECIFIED orcid.org/0000-0001-6070-9490 UNSPECIFIED Lescan, Mario UNSPECIFIED UNSPECIFIED UNSPECIFIED Doemland, Marco UNSPECIFIED UNSPECIFIED UNSPECIFIED Mustafi, Migdat UNSPECIFIED UNSPECIFIED UNSPECIFIED Jungmann, Florian UNSPECIFIED UNSPECIFIED UNSPECIFIED Jorg, Tobias UNSPECIFIED UNSPECIFIED UNSPECIFIED Halloum, Nancy UNSPECIFIED UNSPECIFIED UNSPECIFIED Dorweiler, Bernhard UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-311054
DOI:	10.1371/journal.pone.0240560
Journal or Publication Title:	PLoS One
Volume:	15
Number:	11
Date:	2020
Publisher:	PUBLIC LIBRARY SCIENCE
Place of Publication:	SAN FRANCISCO
ISSN:	1932-6203
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language OUTCOMES; MULTICENTER; EXPERIENCE; ACCESS; RISK Multiple languages Multidisciplinary Sciences Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/31105