Parosmia is Associated with Relevant Olfactory Recovery After Olfactory Training

Liu, David T., Sabha, Maha, Damm, Michael, Philpott, Carl ORCID: 0000-0002-1125-3236, Oleszkiewicz, Anna, Haehner, Antje and Hummel, Thomas . Parosmia is Associated with Relevant Olfactory Recovery After Olfactory Training. Laryngoscope. HOBOKEN: WILEY. ISSN 1531-4995

Full text not available from this repository.

DOI:10.1002/lary.29277

Abstract

Objective/Hypothesis This study aims to determine the association between parosmia and clinically relevant recovery of olfactory function in patients with post-infectious olfactory dysfunction (PIOD) receiving olfactory training. Study Design Retrospective cohort study. Methods This was a retrospective cohort study of patients with PIOD that received olfactory training. Adult patients with the major complaint of quantitative smell loss were recruited and treated at several ENT clinics in German between 2008 and 2018. The outcome was based on the association between smell-loss related factors (including parosmia and phantosmia) and clinically relevant changes in overall and subdimension olfactory function of threshold, discrimination, and identification using binary logistic regression analysis. Results A total of 153 participants with PIOD were included. Clinically relevant improvements in overall olfactory function were more likely in those that had lower baseline olfactory function. Relevant improvements in discrimination function were more likely in those that had lower baseline olfactory function and those that had parosmia at the initial visit. Similarly, relevant improvements in odor identification were more likely in those that had a lower baseline olfactory function and in those who had parosmia at the first visit. Clinically significant improvements in odor threshold were more likely in those who were older in age. Conclusions This study demonstrated that the presence of parosmia is associated with clinically relevant recovery in olfactory discrimination and identification function in patients with PIOD receiving olfactory training. Level of Evidence 4 Laryngoscope, 2020

Item Type:

Journal Article

Creators:

Creators	Email	ORCID	ORCID Put Code
Liu, David T.	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Sabha, Maha	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Damm, Michael	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Philpott, Carl	UNSPECIFIED	orcid.org/0000-0002-1125-3236	UNSPECIFIED
Oleszkiewicz, Anna	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Haehner, Antje	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Hummel, Thomas	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED