Universität zu Köln

Oertel, M., Elsayad, K., Engenhart-Cabillic, R., Reinartz, G., Baues, C., Schmidberger, H., Vordermark, D., Marnitz, S., Lukas, P., Ruebe, C., Engert, A., Lenz, G. and Eich, H. T. (2020). Radiation treatment of hemato-oncological patients in times of the COVID-19 pandemic Expert recommendations from the radiation oncology panels of the German Hodgkin Study Group and the German Lymphoma Alliance. Strahlenther. Onkol., 196 (12). S. 1096 - 1103. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1439-099X

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Abstract

Purpose The coronavirus pandemic is affecting global health systems, endangering daily patient care. Hemato-oncological patients are particularly vulnerable to infection, requiring decisive recommendations on treatment and triage. The aim of this survey amongst experts on radiation therapy (RT) for lymphoma and leukemia is to delineate typical clinical scenarios and to provide counsel for high-quality care. Methods A multi-item questionnaire containing multiple-choice and free-text questions was developed in a peer-reviewed process and sent to members of the radiation oncology panels of the German Hodgkin Study Group and the German Lymphoma Alliance. Answers were assessed online and analyzed centrally. Results Omission of RT was only considered in a minority of cases if alternative treatment options were available. Hypofractionated regimens and reduced dosages may be used for indolent lymphoma and fractures due to multiple myeloma. Overall, there was a tendency to shorten RT rather than to postpone or omit it. Even in case of critical resource shortage, panelists agreed to start emergency RT for typical indications (intracranial pressure, spinal compression, superior vena cava syndrome) within 24-h. Possible criteria to consider for patient triage are the availability of (systemic) options, the underlying disease dynamic, and the treatment rationale (curative/palliative). Conclusion RT for hemato-oncological patients receives high-priority and should be maintained even in later stages of the pandemic. Hypofractionation and shortened treatment schedules are feasible options for well-defined constellations, but have to be discussed in the clinical context.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Oertel, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Elsayad, K. UNSPECIFIED UNSPECIFIED UNSPECIFIED Engenhart-Cabillic, R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Reinartz, G. UNSPECIFIED UNSPECIFIED UNSPECIFIED Baues, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schmidberger, H. UNSPECIFIED UNSPECIFIED UNSPECIFIED Vordermark, D. UNSPECIFIED UNSPECIFIED UNSPECIFIED Marnitz, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Lukas, P. UNSPECIFIED UNSPECIFIED UNSPECIFIED Ruebe, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Engert, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Lenz, G. UNSPECIFIED UNSPECIFIED UNSPECIFIED Eich, H. T. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-314027
DOI:	10.1007/s00066-020-01705-w
Journal or Publication Title:	Strahlenther. Onkol.
Volume:	196
Number:	12
Page Range:	S. 1096 - 1103
Date:	2020
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1439-099X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language DOSE RADIOTHERAPY; THERAPY; PLASMACYTOMA; GUIDELINES Multiple languages Oncology; Radiology, Nuclear Medicine & Medical Imaging Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/31402