Universität zu Köln

Salunkhe, Gayatri, Feige, Bernd, Saville, Christopher W. N., Stefanou, Maria Elena ORCID: 0000-0001-6469-2876, Linden, David, Bender, Stephan, Berger, Andrea, Smyrnis, Nikolaos, Biscaldi, Monica and Klein, Christoph (2020). Dissociating Slow Responses From Slow Responding. Front. Psychiatry, 11. LAUSANNE: FRONTIERS MEDIA SA. ISSN 1664-0640

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Abstract

Increased Intra-Subject Variability (ISV) is a candidate endophenotype of ADHD. ISV's relationship with response speed is highly relevant for ADHD as patients are highly variable but typically no slower than controls. This brief report addresses the relationship between variability and speed by employing dimensional analyses for differentiated performance measures, with a particular focus on the ex-Gaussian measures, across relevant ADHD studies and in young healthy adults (N = 70). For both patients with ADHD and healthy adults, we found that reaction time standard deviation and mean reaction time were strongly correlated, thus failing to dissociate, but ex-Gaussian tau (tau) shared only little variance with Gaussian mu (mu), thus dissociating slow responses (tau) from response speed or-if given-slow responding (mu). Our results highlight the utility of employing the ex-Gaussian measures to disentangle ISV and speed, particularly for ADHD data as patients make more slow responses but are not overall slower than typical controls.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Salunkhe, Gayatri UNSPECIFIED UNSPECIFIED UNSPECIFIED Feige, Bernd UNSPECIFIED UNSPECIFIED UNSPECIFIED Saville, Christopher W. N. UNSPECIFIED UNSPECIFIED UNSPECIFIED Stefanou, Maria Elena UNSPECIFIED orcid.org/0000-0001-6469-2876 UNSPECIFIED Linden, David UNSPECIFIED UNSPECIFIED UNSPECIFIED Bender, Stephan UNSPECIFIED UNSPECIFIED UNSPECIFIED Berger, Andrea UNSPECIFIED UNSPECIFIED UNSPECIFIED Smyrnis, Nikolaos UNSPECIFIED UNSPECIFIED UNSPECIFIED Biscaldi, Monica UNSPECIFIED UNSPECIFIED UNSPECIFIED Klein, Christoph UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-315804
DOI:	10.3389/fpsyt.2020.505800
Journal or Publication Title:	Front. Psychiatry
Volume:	11
Date:	2020
Publisher:	FRONTIERS MEDIA SA
Place of Publication:	LAUSANNE
ISSN:	1664-0640
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language REACTION-TIME VARIABILITY; ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; EX-GAUSSIAN DISTRIBUTION; INTRAINDIVIDUAL VARIABILITY; EVENT RATE; ADHD; CHILDREN; PERFORMANCE; FLUCTUATIONS; GENOTYPE Multiple languages Psychiatry Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/31580