Rongisch, R., Koll, P. and Eming, S. A. (2020). Targeted therapies in Pyoderma gangrenosum: deciphering pathophysiology and improving disease management. Hautarzt, 71 (11). S. 880 - 887. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-1173
Full text not available from this repository.Abstract
The immune response is a central process during wound healing. Malfunctions often lead to chronic inflammation, barrier disorders, and ulcerations of the skin. The underlying pathomechanisms are complex and the subject of current dermatological research. The care of wound healing disorders is still inadequate and urgently needs improved therapy concepts. For several years now, the development of modern immunomodulators has enabled the targeted regulation of specific signaling cascades, and their effectiveness in the treatment of wound healing disorders has been proven in numerous case studies. Thus, their use not only leads to more efficient therapeutic approaches, but also provides deeper insight into the pathomechanistic importance of specific signaling pathways in inflammatory and degenerative diseases of the skin, which are poorly understood so far. Pyoderma gangrenosum, an autoinflammatory disease, provides a good example to illustrate the progress in therapy and pathomechanistic understanding through the use of new immunomodulators and is explained in more detail in the following article.
| Item Type: | Journal Article | ||||||||||||||||
| Creators: |
|
||||||||||||||||
| URN: | urn:nbn:de:hbz:38-317937 | ||||||||||||||||
| DOI: | 10.1007/s00105-020-04697-x | ||||||||||||||||
| Journal or Publication Title: | Hautarzt | ||||||||||||||||
| Volume: | 71 | ||||||||||||||||
| Number: | 11 | ||||||||||||||||
| Page Range: | S. 880 - 887 | ||||||||||||||||
| Date: | 2020 | ||||||||||||||||
| Publisher: | SPRINGER HEIDELBERG | ||||||||||||||||
| Place of Publication: | HEIDELBERG | ||||||||||||||||
| ISSN: | 1432-1173 | ||||||||||||||||
| Language: | German | ||||||||||||||||
| Faculty: | Unspecified | ||||||||||||||||
| Divisions: | Unspecified | ||||||||||||||||
| Subjects: | no entry | ||||||||||||||||
| Uncontrolled Keywords: |
|
||||||||||||||||
| URI: | http://kups.ub.uni-koeln.de/id/eprint/31793 |
Downloads
Downloads per month over past year
Altmetric
Export
Actions (login required)
 |
View Item |