Universität zu Köln

Hedergott, Andrea, Pink-Theofylaktopoulos, Ursula, Neugebauer, Antje and Fricke, Julia (2021). Tendon elongation with bovine pericardium in strabismus surgery-indications beyond Graves' orbitopathy. Graefes Arch. Clin. Exp. Ophthalmol., 259 (1). S. 145 - 156. NEW YORK: SPRINGER. ISSN 1435-702X

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Abstract

Background For some patients with complex ocular motility disorders, conventional strabismus surgery is insufficient. Surgery with tendon elongation allows correction of larger angles and maintains a sufficient arc of contact for rectus muscles. This study reports results for tendon elongation with bovine pericardium (Tutopatch (R)) in indications other than Graves' orbitopathy in which it is already widely used. Methods We reviewed the records of all patients who underwent surgery with Tutopatch (R) in our institution. Angles of squint and head postures were analyzed preoperatively, on the first postoperative day, and in the long term (median 9 weeks after the operation). Patients with Graves' orbitopathy were excluded. Results From 2011 to 2018, the procedures on 58 eyes of 54 patients (35 females, median age 35 years (3-75)) met the inclusion criteria. Horizontal rectus muscle surgery (53 eyes) was conducted on patients with residual strabismus (13), Duane's retraction syndrome with eso- (type I: 16)/exodeviation (type II: 2, type III: 1), 6th (7)/3rd nerve palsy (7), Mobius syndrome (2), congenital fibrosis of the extraocular muscles type 3A (CFEOM3A, TUBB3 mutation) (4), and orbital apex syndrome (1). Vertical rectus muscle surgery (5 eyes) was conducted on patients with myasthenia (1), vertical tropia after orbital floor fracture (1), CFEOM1 (2), and Parry-Romberg syndrome (1). 42 eyes had prior eye muscle surgery (1-5 procedures, median 1). Out of 45 patients with postoperative long-term data, 43 showed an angle reduction. Fifty-one percent had an angle of 10 Delta (prism diopter) or less, one had a significant over-effect, and 10 had revision surgery. For the heterogeneous group of residual eso- and exotropias, the median absolute horizontal angle was reduced from 35 Delta (16 to 45 Delta) to 9 Delta (0 to 40 Delta), for Duane's retraction syndrome from 27.5 Delta (9 to 40 Delta) to 7 Delta (0 to 40 Delta), and for sixth and third nerve palsies from 43 Delta (20 to 75 Delta) to 18 Delta (4 to 40 Delta). For 3 patients with vertical rectus muscle surgery, the median absolute vertical angle was reduced from 30 Delta (20 to 45 Delta) to 4 Delta (1 to 22 Delta). The motility range was shifted in the direction contrary to the elongated muscle in all subgroups. A considerable reduction of the excursion into the field of action of the elongated muscle had to be registered. Conclusions Strabismus surgery with bovine pericardium introduces new surgical options for complicated revisions and for rare and complex oculomotor dysfunctions. Yet, it has to be recognized that this type of surgery aiming at maximum effects, despite preservation or restitution of the arc of contact, leads to reduction of the excursion into the field of action of the elongated muscle. Furthermore, dose finding can be difficult depending on the underlying pathology and more than one intervention might be necessary for optimal results.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Hedergott, Andrea UNSPECIFIED UNSPECIFIED UNSPECIFIED Pink-Theofylaktopoulos, Ursula UNSPECIFIED UNSPECIFIED UNSPECIFIED Neugebauer, Antje UNSPECIFIED UNSPECIFIED UNSPECIFIED Fricke, Julia UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-318833
DOI:	10.1007/s00417-020-04939-7
Journal or Publication Title:	Graefes Arch. Clin. Exp. Ophthalmol.
Volume:	259
Number:	1
Page Range:	S. 145 - 156
Date:	2021
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1435-702X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language Ophthalmology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/31883