Universität zu Köln

Widder, Randolf Alexander, Hild, Matthias, Dietlein, Thomas Stefan, Kuehnrich, Pia, Rennings, Corinna, Szumniak, Alexander, Lappas, Alexandra and Roessler, Gernot Franz . Trabectome, trabecular aspiration and phacoemulsification in a triple procedure for treating exfoliation glaucoma: A long-term follow-up. Eur. J. Ophthalmol.. LONDON: SAGE PUBLICATIONS LTD. ISSN 1724-6016

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Abstract

Purpose: This study investigates the long-term intraocular pressure (IOP) lowering potential, risk profile and success rate of a triple procedure comprising phacoemulsification, trabecular aspiration and trabectome (Microsurgical Technology, Redmond, WA, USA) for treating exfoliation glaucoma. Methods: A total of 117 eyes of 117 patients with exfoliation glaucoma underwent a combination of phacoemulsification, trabectome and trabecular aspiration. They were followed up for up to 7 years. The success rates were designated according to criteria based on the Tube versus Trabeculectomy Study and the World Glaucoma Association guidelines: A (no resurgery); B/C (IOP < 21/18 mmHg, no resurgery, IOP reduction > 20%); D (IOP <= 15 mmHg, no resurgery, IOP reduction > 40%). Results: The mean follow-up period was 46 months. IOP showed a 38% reduction from 24.5 +/- 6.1 to 15.2 +/- 3.6 mmHg (p< 0.0001). The Medication Score decreased by 23% from 2.2 +/- 0.9 to 1.7 +/- 1.0 (p< 0.0001). The success rates were 87, 76, 74 and 38% according to criteria A, B, C and D. In eyes with an initial IOP of >30 mmHg, a 57% reduction from 34.2 +/- 4.4 to 14.8 +/- 3.2 mmHg (p< 0.0001) was observed, and the success rates were 91, 91, 82 and 59% for criteria A, B, C and D, respectively. Discussion: We conclude that the triple procedure may effectively lower IOP in patients with exfoliation glaucoma over a mean follow-up period of 46 months without significant side effects. Therefore, the triple procedure may serve as first-line surgery for patients with exfoliation and cataract, even with a high initial IOP.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Widder, Randolf Alexander UNSPECIFIED UNSPECIFIED UNSPECIFIED Hild, Matthias UNSPECIFIED UNSPECIFIED UNSPECIFIED Dietlein, Thomas Stefan UNSPECIFIED UNSPECIFIED UNSPECIFIED Kuehnrich, Pia UNSPECIFIED UNSPECIFIED UNSPECIFIED Rennings, Corinna UNSPECIFIED UNSPECIFIED UNSPECIFIED Szumniak, Alexander UNSPECIFIED UNSPECIFIED UNSPECIFIED Lappas, Alexandra UNSPECIFIED UNSPECIFIED UNSPECIFIED Roessler, Gernot Franz UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-319311
DOI:	10.1177/1120672120956505
Journal or Publication Title:	Eur. J. Ophthalmol.
Publisher:	SAGE PUBLICATIONS LTD
Place of Publication:	LONDON
ISSN:	1724-6016
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language AB-INTERNO TRABECULECTOMY; CLEAR CORNEA PHACOEMULSIFICATION; PSEUDOEXFOLIATIVE GLAUCOMA; INTRAOCULAR-PRESSURE; SUTURE TRABECULOTOMY; COMBINED CATARACT; SURGERY; CANALOPLASTY; OUTCOMES Multiple languages Ophthalmology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/31931