Universität zu Köln

Jenks, Jeffrey D., Cornely, Oliver A., Chen, Sharon C-A, Thompson, George R., III and Hoenigl, Martin ORCID: 0000-0002-1653-2824 (2020). Breakthrough invasive fungal infections: Who is at risk? Mycoses, 63 (10). S. 1021 - 1033. HOBOKEN: WILEY. ISSN 1439-0507

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Abstract

The epidemiology of invasive fungal infections (IFIs) in immunocompromised individuals has changed over the last few decades, partially due to the increased use of antifungal agents to prevent IFIs. Although this strategy has resulted in an overall reduction in IFIs, a subset of patients develop breakthrough IFIs with substantial morbidity and mortality in this population. Here, we review the most significant risk factors for breakthrough IFIs in haematology patients, solid organ transplant recipients, and patients in the intensive care unit, focusing particularly on host factors, and highlight areas that require future investigation.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Jenks, Jeffrey D. UNSPECIFIED UNSPECIFIED UNSPECIFIED Cornely, Oliver A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Chen, Sharon C-A UNSPECIFIED UNSPECIFIED UNSPECIFIED Thompson, George R., III UNSPECIFIED UNSPECIFIED UNSPECIFIED Hoenigl, Martin UNSPECIFIED orcid.org/0000-0002-1653-2824 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-319790
DOI:	10.1111/myc.13148
Journal or Publication Title:	Mycoses
Volume:	63
Number:	10
Page Range:	S. 1021 - 1033
Date:	2020
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1439-0507
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language BRONCHOALVEOLAR LAVAGE FLUID; ORGAN TRANSPLANT RECIPIENTS; MOLD INFECTIONS; HEMATOLOGICAL MALIGNANCIES; CANDIDA-ALBICANS; PULMONARY ASPERGILLOSIS; ANTIFUNGAL PROPHYLAXIS; PLASMA-CONCENTRATIONS; NEUTROPENIC PATIENTS; CANCER-PATIENTS Multiple languages Dermatology; Mycology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/31979