Universität zu Köln

Kaschner, Marius, Lichtenstein, Thorsten, Weiss, Daniel, Turowski, Bernd, Goertz, Lukas, Kluner, Claudia, Schlamann, Marc, Mathys, Christian and Kabbasch, Christoph ORCID: 0000-0003-3712-2258 (2020). The New Fully Radiopaque Aperio Hybrid Stent Retriever: Efficient and Safe? An Early Multicenter Experience. World Neurosurg., 141. S. E278 - 11. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1878-8769

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Abstract

OBJECTIVE: To investigate the visibility, safety, and efficacy of the full-length radiopaque Aperio Hybrid stent retriever (APH) in mechanical thrombectomy of large vessel occlusions. METHODS: Multicentric retrospective analysis of patients with stroke, treated with the APH due to an acute ischemic stroke by large vessel occlusions in the anterior or posterior circulation, was performed. We focused on technical and angiographic parameters including device visibility, perfusion results (modified thrombolysis in cerebral infarction scale [mTICI]), procedural times, periprocedural complications, and favorable clinical outcome (modified Rankin Scale, 0-2) at discharge and after 90 days. RESULTS: A total of 48 patients (male: n = 22, 45.8%, mean age 73 years [standard deviation (SD), +/- 15], median baseline National Institutes of Health Stroke Scale: 15 [2-36], n = 25, 52.1% received additional intravenous thrombolytics) were treated with the APH with a mean number of 2 device passes (SD, +3) in APH-only cases (n = 41). The median time from groin puncture to the final mTICI was 54 minutes (SD, +33). In 46 patients (95.8%), mTICI 2be-3 was achieved (mTICI 2c, 12.5%; mTICI 3, 47.9%). Favorable outcome (modified Rankin Scale <2) was achieved in 15 (32.6%) patients at discharge and in 11 of the 30 (36.7%) patients available for 90-day follow-up. Symptomatic intracranial hemorrhage was recorded in 3 of 48 cases (6.3%). Difficulties during device delivery and/or deployment occurred in 6.3% (3 of 48). APH-related adverse events did not occur. APH radiopacity was rated as good and very good in 97.9% (47 of 48). CONCLUSIONS: Mechanical thrombectomy with the APH appeared feasible, efficient, and safe. Full-length device radiopacity may facilitate thrombectomy or support to adapt the course of action during retrieval, if required.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Kaschner, Marius UNSPECIFIED UNSPECIFIED UNSPECIFIED Lichtenstein, Thorsten UNSPECIFIED UNSPECIFIED UNSPECIFIED Weiss, Daniel UNSPECIFIED UNSPECIFIED UNSPECIFIED Turowski, Bernd UNSPECIFIED UNSPECIFIED UNSPECIFIED Goertz, Lukas UNSPECIFIED UNSPECIFIED UNSPECIFIED Kluner, Claudia UNSPECIFIED UNSPECIFIED UNSPECIFIED Schlamann, Marc UNSPECIFIED UNSPECIFIED UNSPECIFIED Mathys, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Kabbasch, Christoph UNSPECIFIED orcid.org/0000-0003-3712-2258 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-321930
DOI:	10.1016/j.wneu.2020.05.104
Journal or Publication Title:	World Neurosurg.
Volume:	141
Page Range:	S. E278 - 11
Date:	2020
Publisher:	ELSEVIER SCIENCE INC
Place of Publication:	NEW YORK
ISSN:	1878-8769
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ISCHEMIC-STROKE; SUCCESSFUL RECANALIZATION; THROMBECTOMY; THERAPY; DEVICE Multiple languages Clinical Neurology; Surgery Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/32193