Universität zu Köln

Ehret, Felix, Kufeld, Markus, Fuerweger, Christoph, Haidenberger, Alfred, Schichor, Christian, Lehrke, Ralph, Fichte, Susanne, Senger, Carolin, Bleif, Martin, Ruess, Daniel, Ruge, Maximilian, Tonn, Joerg-Christian, Muacevic, Alexander and Hempel, John-Martin (2021). Image-guidedrobotic radiosurgery for glomus jugulare tumors-Multicenter experience and review of the literature. Head Neck-J. Sci. Spec. Head Neck, 43 (1). S. 35 - 48. HOBOKEN: WILEY. ISSN 1097-0347

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Abstract

Background Glomus jugulare tumors (GJTs) are challenging to treat due to their vascularization and location. This analysis evaluates the effectiveness and safety of image-guided robotic radiosurgery (RRS) for GJTs in a multicenter study and reviews the existing radiosurgical literature. Methods We analyzed outcome data from 101 patients to evaluate local control (LC), changes in pretreatment deficits, and toxicity. Moreover, radiosurgical studies for GJTs have been reviewed. Results After a median follow-up of 35 months, the overall LC was 99%. Eighty-eight patients were treated with a single dose, 13 received up to 5 fractions. The median tumor volume was 5.6 cc; the median treatment dose for single-session treatments is 16 Gy, and for multisession treatments is 21 Gy. Fifty-six percentage of patients experienced symptom improvement or recovered entirely. Conclusions RRS is an effective primary and secondary treatment option for GJTs. The available literature suggests that radiosurgery is a treatment option for most GJTs.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Ehret, Felix UNSPECIFIED UNSPECIFIED UNSPECIFIED Kufeld, Markus UNSPECIFIED UNSPECIFIED UNSPECIFIED Fuerweger, Christoph UNSPECIFIED UNSPECIFIED UNSPECIFIED Haidenberger, Alfred UNSPECIFIED UNSPECIFIED UNSPECIFIED Schichor, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Lehrke, Ralph UNSPECIFIED UNSPECIFIED UNSPECIFIED Fichte, Susanne UNSPECIFIED UNSPECIFIED UNSPECIFIED Senger, Carolin UNSPECIFIED UNSPECIFIED UNSPECIFIED Bleif, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED Ruess, Daniel UNSPECIFIED UNSPECIFIED UNSPECIFIED Ruge, Maximilian UNSPECIFIED UNSPECIFIED UNSPECIFIED Tonn, Joerg-Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Muacevic, Alexander UNSPECIFIED UNSPECIFIED UNSPECIFIED Hempel, John-Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-322581
DOI:	10.1002/hed.26439
Journal or Publication Title:	Head Neck-J. Sci. Spec. Head Neck
Volume:	43
Number:	1
Page Range:	S. 35 - 48
Date:	2021
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1097-0347
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language GAMMA-KNIFE RADIOSURGERY; STEREOTACTIC RADIOSURGERY; NECK PARAGANGLIOMAS; SURGICAL RESECTION; MANAGEMENT; HEAD; OUTCOMES; SURGERY; RADIOTHERAPY; TOXICITY Multiple languages Otorhinolaryngology; Surgery Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/32258