Universität zu Köln

Yagdiran, Ayla ORCID: 0000-0002-1723-5995, Otto-Lambertz, Christina, Lingscheid, Kristina Michaela, Sircar, Krishnan, Samel, Christina, Scheyerer, Max Joseph, Zarghooni, Kourosh, Eysel, Peer, Sobottke, Rolf, Jung, Norma and Siewe, Jan . Quality of life and mortality after surgical treatment for vertebral osteomyelitis (VO): a prospective study. Eur. Spine J.. NEW YORK: SPRINGER. ISSN 1432-0932

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Abstract

Purpose Vertebral osteomyelitis (VO) has a high mortality and leads to chronic pain and functional disability. Surgical treatment is often necessary. To date, little is known about the consequences of surgery on patient outcome. The aim of this study was to determine the quality of life (QoL) and mortality rates of surgically treated VO patients for a period of 2 years. Methods Patients with VO undergoing surgical treatment in a tertiary referral hospital from 2008 to 2015 were included prospectively. Data were collected before (T0) as well as 1 year (T1) and 2 years (T2) post-surgery. Within the European Spine Tango registry, prospective patient and QoL data were collected using validated outcome scores: Oswestry Disability Index, Short Form 36/EuroQol, Visual Analog Scale, and Core Outcome Measures Index. Results From 195 patients surgically treated for VO, QoL data were available from 136 patients atT0, 100 patients atT1, and 82 patients atT2, respectively. The 1- and 2-year mortality rates were 20% and 23%. Mainly all QoL outcome scores showed significant improvement atT1 and did not change significantly fromT1 toT2. Conclusion Surgical treatment of VO patients leads to significantly improved QoL. Nevertheless, QoL levels were below those of the general population. Our results underscore that spine disability questionnaires measuring QoL are mandatory to demonstrate comprehensively the severity of this entity. Our study confirms a high mortality and points out the role of VO as a potentially life-threatening condition.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Yagdiran, Ayla UNSPECIFIED orcid.org/0000-0002-1723-5995 UNSPECIFIED Otto-Lambertz, Christina UNSPECIFIED UNSPECIFIED UNSPECIFIED Lingscheid, Kristina Michaela UNSPECIFIED UNSPECIFIED UNSPECIFIED Sircar, Krishnan UNSPECIFIED UNSPECIFIED UNSPECIFIED Samel, Christina UNSPECIFIED UNSPECIFIED UNSPECIFIED Scheyerer, Max Joseph UNSPECIFIED UNSPECIFIED UNSPECIFIED Zarghooni, Kourosh UNSPECIFIED UNSPECIFIED UNSPECIFIED Eysel, Peer UNSPECIFIED UNSPECIFIED UNSPECIFIED Sobottke, Rolf UNSPECIFIED UNSPECIFIED UNSPECIFIED Jung, Norma UNSPECIFIED UNSPECIFIED UNSPECIFIED Siewe, Jan UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-328150
DOI:	10.1007/s00586-020-06519-z
Journal or Publication Title:	Eur. Spine J.
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1432-0932
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language LONG-TERM MORTALITY; INFECTIOUS SPONDYLODISCITIS; PYOGENIC SPONDYLODISCITIS; DIAGNOSIS Multiple languages Clinical Neurology; Orthopedics Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/32815