Universität zu Köln

Veronese, Nicola ORCID: 0000-0002-9328-289X, Cella, Alberto, Cruz-Jentoft, Alfonso J. ORCID: 0000-0001-7628-4861, Polidori, Maria Cristina, Mattace-Raso, Francesco, Paccalin, Marc, Topinkova, Eva, Greco, Antonio, Mangoni, Arduino A., Daragjati, Julia, Siri, Giacomo ORCID: 0000-0001-8006-0668 and Pilotto, Alberto (2020). Enteral tube feeding and mortality in hospitalized older patients: A multicenter longitudinal study. Clin. Nutr., 39 (5). S. 1608 - 1613. EDINBURGH: CHURCHILL LIVINGSTONE. ISSN 1532-1983

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Abstract

Background & aims: The literature regarding enteral nutrition and mortality in older frail people is limited and still conflicting. Moreover, the potential role of comprehensive geriatric assessment is poorly explored. We therefore aimed to investigate whether the Multidimensional Prognostic Index (MPI), an established tool that assesses measures of frailty and predicts mortality, may help physicians in identifying patients in whom ETF (enteral tube feeding) is effective in terms of reduced mortality. Methods: Observational, longitudinal, multicenter study with one year of follow-up. Data regarding ETF were recorded through medical records. A standardized comprehensive geriatric assessment was used to calculate the MPI. Participants were divided in low (MPI-1), moderate (MPI-2) or severe (MPI-3) risk of mortality. Data regarding mortality were recorded through administrative information. Results: 1064 patients were included, with 79 (13 in MPI 1-2 and 66 in MPI-3 class) receiving ETF. In multivariable analysis, patients receiving ETF experienced a higher risk of death (odds ratio, OR = 2.00; 95% confidence intervals, CI: 1.19-3.38). However, after stratifying for their MPI at admission, mortality was higher in MPI-3 class patients (OR = 2.03; 95%CI: 1.09-3.76), but not in MPI 1-2 class patients (OR = 1.51; 95%CI: 0.44-5.25). The use of propensity score confirmed these findings. Conclusions: ETF is associated with a higher risk of death. However, this is limited to more frail patients, suggesting the importance of the MPI in the prognostic evaluation of ETF. (C) 2019 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Veronese, Nicola UNSPECIFIED orcid.org/0000-0002-9328-289X UNSPECIFIED Cella, Alberto UNSPECIFIED UNSPECIFIED UNSPECIFIED Cruz-Jentoft, Alfonso J. UNSPECIFIED orcid.org/0000-0001-7628-4861 UNSPECIFIED Polidori, Maria Cristina UNSPECIFIED UNSPECIFIED UNSPECIFIED Mattace-Raso, Francesco UNSPECIFIED UNSPECIFIED UNSPECIFIED Paccalin, Marc UNSPECIFIED UNSPECIFIED UNSPECIFIED Topinkova, Eva UNSPECIFIED UNSPECIFIED UNSPECIFIED Greco, Antonio UNSPECIFIED UNSPECIFIED UNSPECIFIED Mangoni, Arduino A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Daragjati, Julia UNSPECIFIED UNSPECIFIED UNSPECIFIED Siri, Giacomo UNSPECIFIED orcid.org/0000-0001-8006-0668 UNSPECIFIED Pilotto, Alberto UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-335547
DOI:	10.1016/j.clnu.2019.07.011
Journal or Publication Title:	Clin. Nutr.
Volume:	39
Number:	5
Page Range:	S. 1608 - 1613
Date:	2020
Publisher:	CHURCHILL LIVINGSTONE
Place of Publication:	EDINBURGH
ISSN:	1532-1983
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language MULTIDIMENSIONAL PROGNOSTIC INDEX; GUIDELINES; VALIDATION; ADULTS; CARE Multiple languages Nutrition & Dietetics Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/33554