Abdullayev, N., Maus, V, Mpotsaris, A., Henning, T. D., Goertz, L., Borggrefe, J., Chang, D. H., Onur, Oa, Liebig, T., Schlamann, M. and Kabbasch, C. (2020). Comparative analysis of CGUARD embolic prevention stent with Casper-RX and Wallstent for the treatment of carotid artery stenosis. J. Clin. Neurosci., 75. S. 117 - 122. OXFORD: ELSEVIER SCI LTD. ISSN 1532-2653

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Abstract

Stent protected Angioplasty of extracranial carotid artery stenosis using the dual-layered CGUARD stent is a novel treatment option. In this study we evaluate the feasibility and the safety of the CGUARD in symptomatic and asymptomatic patients in comparison to Casper-RX and Wallstent. This is a multi-center study of consecutive patients treated with the CGUARD, Casper-RX and Wallstent at two German high volume neurovascular centers between April 2017 and May 2018. Patient characteristics, neuroimaging data and angiographic outcome were retrospectively analyzed. The primary end points of the study were acute occlusion of the carotid stent and symptomatic intracerebral hemorrhage (sICH). Carotid artery stenting was performed in 76 patients; of those 26 (34%) were treated with the CGUARD, 25 (33%) with Casper-RX, and 25 (33%) with Wallstent. In 58/76 (76%) cases carotid artery stenosis was symptomatic with a median baseline National Institutes of Health Stroke Scale of 4. Angioplasty and stenting as part of a mechanical thrombectomy for acute ischemic stroke was performed in 25/76 (33%) patients. Baseline patient characteristics were similar between the treatment groups, except for a higher portion of scheduled cases in the Casper-RX group. There were no significant differences in the rate of acute in stent occlusions (CGUARD, 2/26 (8%); Casper-RX, 1/25(4%), Wallstent, 1/25 (4%)) and postinterventional sICH (1/26 (4%), 0/25(0%), 0/25 (0%)). Clinical outcome at discharge did not differ between groups. Treatment of carotid artery stenosis using CGUARD is feasible with a good safety profile comparable to that of Casper-RX and Wallstent. (C) 2020 Elsevier Ltd. All rights reserved.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Abdullayev, N.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Maus, VUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mpotsaris, A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Henning, T. D.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Goertz, L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Borggrefe, J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Chang, D. H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Onur, OaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Liebig, T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schlamann, M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kabbasch, C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-335893
DOI: 10.1016/j.jocn.2020.03.008
Journal or Publication Title: J. Clin. Neurosci.
Volume: 75
Page Range: S. 117 - 122
Date: 2020
Publisher: ELSEVIER SCI LTD
Place of Publication: OXFORD
ISSN: 1532-2653
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
STROKE; AREAMultiple languages
Clinical Neurology; NeurosciencesMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/33589

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