Universität zu Köln

Styczen, Hanna ORCID: 0000-0002-9623-4156, Maus, Volker, Hesse, Amelie C., Goertz, Lukas, Fischer, Sebastian, Riedel, Christian, Forsting, Michael, Radbruch, Alexander and Behme, Daniel (2020). Impact of early division of the middle cerebral artery on outcome following mechanical thrombectomy. Interv. Neuroradiol., 26 (4). S. 389 - 396. THOUSAND OAKS: SAGE PUBLICATIONS INC. ISSN 2385-2011

Full text not available from this repository.

Abstract

Background Mechanical thrombectomy has become the standard care for acute ischemic stroke caused by large vessel occlusion. However, complete reperfusion cannot be achieved in all cases, and several factors influencing the results of mechanical thrombectomy have been investigated. Among others, a tortuous anatomy is associated with lower rates of complete reperfusion. We aimed to investigate whether an early division of the middle cerebral artery has an impact on reperfusion results in mechanical thrombectomy. Methods Retrospective review of consecutive patients with M1 occlusion treated endovascularly between January 2016 and December 2019 at three tertiary care centers. The study group was dichotomized based on the length of the M1 segment. Early division of the middle cerebral artery was defined as a maximum length of 10 mm of the M1 segment. Primary endpoints were first-pass mTICI scores of 3, >= 2c, and >= 2b. Secondary endpoints contained final reperfusion, number of device-passes, time interval from groin puncture to reperfusion, rate of postinterventional symptomatic intracranial hemorrhage, and frequency of emboli of new territory. Results Among 284 included patients, 70 presented with an early division of the M1 segment (25%). Reperfusion results did not differ significantly between early and late division of M1. A higher rate of symptomatic intracranial hemorrhage was found in the group with an early M1 division treated with aspiration only (14.3% vs. 0%; p = 0.013). Patients with late M1 division had a significantly higher rate of large artery sclerosis (19.2% vs. 8.6%, p = 0.039). Conclusion The anatomic variant of an early division of the middle cerebral artery was not a predictor for incomplete reperfusion.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Styczen, Hanna UNSPECIFIED orcid.org/0000-0002-9623-4156 UNSPECIFIED Maus, Volker UNSPECIFIED UNSPECIFIED UNSPECIFIED Hesse, Amelie C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Goertz, Lukas UNSPECIFIED UNSPECIFIED UNSPECIFIED Fischer, Sebastian UNSPECIFIED UNSPECIFIED UNSPECIFIED Riedel, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Forsting, Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED Radbruch, Alexander UNSPECIFIED UNSPECIFIED UNSPECIFIED Behme, Daniel UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-336362
DOI:	10.1177/1591019920920987
Journal or Publication Title:	Interv. Neuroradiol.
Volume:	26
Number:	4
Page Range:	S. 389 - 396
Date:	2020
Publisher:	SAGE PUBLICATIONS INC
Place of Publication:	THOUSAND OAKS
ISSN:	2385-2011
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ISCHEMIC-STROKE; RECANALIZATION; THROMBOLYSIS; ANATOMY Multiple languages Clinical Neurology; Radiology, Nuclear Medicine & Medical Imaging Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/33636