Universität zu Köln

Schleberger, Ruben ORCID: 0000-0003-3798-6427, Jularic, Mario, Salzbrunn, Tim, Hacke, Claudia, Schwarzl, Jana M., Hoffmann, Boris A., Steven, Daniel, Willems, Stephan, Lemoine, Marc D. and Meyer, Christian ORCID: 0000-0003-0217-3960 (2020). Outcome of catheter ablation of non-reentrant ventricular arrhythmias in patients with and without structural heart disease. Eur. J. Med. Res., 25 (1). LONDON: BMC. ISSN 2047-783X

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Abstract

Background Catheter ablation of non-reentrant, commonly termed idiopathic ventricular arrhythmias (VA) is highly effective in patients without structural heart disease (SHD). Meanwhile, the outcome of catheter ablation of these arrhythmias in patients with SHD remains unclear. This study sought to characterize the outcome of patients with and without SHD undergoing catheter ablation of non-reentrant VA. Methods In this single-centre study the acute and long-term outcome of 266 consecutive patients undergoing catheter ablation of non-reentrant VA was investigated. In 41.0% of patients a SHD was present (n = 109, 80.7% male, age 59.1 +/- 14.7 years), 59.0% had no SHD (n = 157; 44.0% male, age 49.9 +/- 16.5 years). Results Acute procedural success (absence of spontaneous or provoked VA at the end of procedure and within 48 h after the procedure) was achieved in 89.9% of patients with SHD vs. 94.3% without SHD (p = 0.238). During a mean follow-up of 34.7 +/- 15.1 months a repeat catheter ablation was performed in 19.6% of patients with SHD vs. 13.0% without SHD (p = 0.179). Patients with dilated cardiomyopathy (DCM) were the most likely to require a repeat ablation procedure (32.0% of patients with DCM vs. 13.0% without SHD; p = 0.022). Periprocedural complications occurred in 5.5% of patients with SHD vs. 5.7% without SHD (p > 0.999). All complications were managed without sequelae. Conclusions The outcome of catheter ablation of non-reentrant VA in patients with SHD appears good and is comparable to patients without SHD. A slightly higher rate of repeat ablations was observed in patients with DCM.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Schleberger, Ruben UNSPECIFIED orcid.org/0000-0003-3798-6427 UNSPECIFIED Jularic, Mario UNSPECIFIED UNSPECIFIED UNSPECIFIED Salzbrunn, Tim UNSPECIFIED UNSPECIFIED UNSPECIFIED Hacke, Claudia UNSPECIFIED UNSPECIFIED UNSPECIFIED Schwarzl, Jana M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Hoffmann, Boris A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Steven, Daniel UNSPECIFIED UNSPECIFIED UNSPECIFIED Willems, Stephan UNSPECIFIED UNSPECIFIED UNSPECIFIED Lemoine, Marc D. UNSPECIFIED UNSPECIFIED UNSPECIFIED Meyer, Christian UNSPECIFIED orcid.org/0000-0003-0217-3960 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-340685
DOI:	10.1186/s40001-020-0400-y
Journal or Publication Title:	Eur. J. Med. Res.
Volume:	25
Number:	1
Date:	2020
Publisher:	BMC
Place of Publication:	LONDON
ISSN:	2047-783X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language EUROPEAN-SOCIETY; OUTFLOW TRACT; FOLLOW-UP; TACHYCARDIA; CARDIOMYOPATHY; FIBRILLATION; DYSFUNCTION; PREVENTION; RECOVERY Multiple languages Medicine, Research & Experimental Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/34068