Universität zu Köln

Voltin, Conrad-Amadeus ORCID: 0000-0002-5437-3959, Mettler, Jasmin, Grosse, Jirka, Dietlein, Markus, Baues, Christian, Schmitz, Christine, Borchmann, Peter, Kobe, Carsten and Hellwig, Dirk ORCID: 0000-0002-3056-0143 (2020). FDG-PET Imaging for Hodgkin and Diffuse Large B-Cell Lymphoma-An Updated Overview. Cancers, 12 (3). BASEL: MDPI. ISSN 2072-6694

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Abstract

Since the mid-1990s, F-18-fluorodeoxglucose (FDG)-positron emission tomography (PET) in combination with computed tomography has come to play a prominent role in the management of malignant lymphomas. One of the first PET applications in oncology was the detection of lymphoma manifestations at staging, where it has shown high sensitivity. Nowadays, this imaging modality is also used during treatment to evaluate the individual chemosensitivity and adapt further therapy accordingly. If the end-of-treatment PET is negative, irradiation in advanced-stage Hodgkin lymphoma patients can be safely omitted after highly effective chemotherapy. Thus far, lymphoma response assessment has mainly been performed using visual criteria, such as the Deauville five-point scale, which became the international standard in 2014. However, novel measures such as metabolic tumor volume or total lesion glycolysis have recently been recognized by several working groups and may further increase the diagnostic and prognostic value of FDG-PET in the future.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Voltin, Conrad-Amadeus UNSPECIFIED orcid.org/0000-0002-5437-3959 UNSPECIFIED Mettler, Jasmin UNSPECIFIED UNSPECIFIED UNSPECIFIED Grosse, Jirka UNSPECIFIED UNSPECIFIED UNSPECIFIED Dietlein, Markus UNSPECIFIED UNSPECIFIED UNSPECIFIED Baues, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Schmitz, Christine UNSPECIFIED UNSPECIFIED UNSPECIFIED Borchmann, Peter UNSPECIFIED UNSPECIFIED UNSPECIFIED Kobe, Carsten UNSPECIFIED UNSPECIFIED UNSPECIFIED Hellwig, Dirk UNSPECIFIED orcid.org/0000-0002-3056-0143 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-342007
DOI:	10.3390/cancers12030601
Journal or Publication Title:	Cancers
Volume:	12
Number:	3
Date:	2020
Publisher:	MDPI
Place of Publication:	BASEL
ISSN:	2072-6694
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language POSITRON-EMISSION-TOMOGRAPHY; BONE-MARROW INVOLVEMENT; METABOLIC TUMOR VOLUME; PROGNOSTIC VALUE; FOLLOW-UP; RESPONSE EVALUATION; ADAPTED TREATMENT; 1ST-LINE THERAPY; ELDERLY-PATIENTS; PREDICTIVE-VALUE Multiple languages Oncology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/34200