Universität zu Köln

Yazer, Mark H., Spinella, Philip C., Doyle, Leilani, Kaufman, Richard M., Dunn, Robyn, Hess, John R., Filho, Luiz Amorim, Fontaine, Magali, Gathof, Birgit, Jackson, Bryon, Murphy, Michael F., Pasion, Jeremiah, Raval, Jay S., Rosinski, Kristin, Seheult, Jansen ORCID: 0000-0002-6850-7495, Shih, Andrew W., Sperry, Jason, Staves, Julie, Tuott, Erin E., Ziman, Alyssa and Triulzi, Darrell J. (2020). Transfusion of Uncrossmatched Group O Erythrocyte-containing Products Does Not Interfere with Most ABO Typings. Anesthesiology, 132 (3). S. 525 - 535. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1528-1175

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Abstract

Background: Group O erythrocytes and/or whole blood are used for urgent transfusions in patients of unknown blood type. This study investigated the impact of transfusing increasing numbers of uncrossmatched type O products on the recipient's first in-hospital ABO type. Methods: This was a retrospective cohort study. Results of the first ABO type obtained in adult, non-type O recipients (i.e., types A, B, AB) after receiving at least one unit of uncrossmatched type O erythrocyte-containing product(s) for any bleeding etiology were analyzed along with the number of uncrossmatched type O erythrocyte-containing products administered in the prehospital and/or in hospital setting before the first type and screen sample was drawn. Results: There were 10 institutions that contributed a total of 695 patient records. Among patients who received up to 10 uncrossmatched type O erythrocyte-containing products, the median A antigen agglutination strength in A and AB individuals on forward typing (i.e., testing the recipient's erythrocytes for A and/or B antigens) was the maximum (4+), whereas the median B antigen agglutination strength among B and AB recipients of up to 10 units was 3 to 4+. The median agglutination strength on the reverse type (i.e., testing the recipient's plasma for corresponding anti-A and -B antibodies) was very strong, between 3 and 4+, for recipients of up to 10 units of uncrossmatched erythrocyte-containing products. Overall, the ABO type of 665 of 695 (95.7%; 95% CI, 93.9 to 97.0%) of these patients could be accurately determined on the first type and screen sample obtained after transfusion of uncrossmatched type O erythrocyte-containing products. Conclusions: The transfusion of smaller quantities of uncrossmatched type O erythrocyte-containing products, in particular up to 10 units, does not usually interfere with determining the recipient's ABO type. The early collection of a type and screen sample is important.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Yazer, Mark H. UNSPECIFIED UNSPECIFIED UNSPECIFIED Spinella, Philip C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Doyle, Leilani UNSPECIFIED UNSPECIFIED UNSPECIFIED Kaufman, Richard M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Dunn, Robyn UNSPECIFIED UNSPECIFIED UNSPECIFIED Hess, John R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Filho, Luiz Amorim UNSPECIFIED UNSPECIFIED UNSPECIFIED Fontaine, Magali UNSPECIFIED UNSPECIFIED UNSPECIFIED Gathof, Birgit UNSPECIFIED UNSPECIFIED UNSPECIFIED Jackson, Bryon UNSPECIFIED UNSPECIFIED UNSPECIFIED Murphy, Michael F. UNSPECIFIED UNSPECIFIED UNSPECIFIED Pasion, Jeremiah UNSPECIFIED UNSPECIFIED UNSPECIFIED Raval, Jay S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Rosinski, Kristin UNSPECIFIED UNSPECIFIED UNSPECIFIED Seheult, Jansen UNSPECIFIED orcid.org/0000-0002-6850-7495 UNSPECIFIED Shih, Andrew W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Sperry, Jason UNSPECIFIED UNSPECIFIED UNSPECIFIED Staves, Julie UNSPECIFIED UNSPECIFIED UNSPECIFIED Tuott, Erin E. UNSPECIFIED UNSPECIFIED UNSPECIFIED Ziman, Alyssa UNSPECIFIED UNSPECIFIED UNSPECIFIED Triulzi, Darrell J. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-342121
DOI:	10.1097/ALN.0000000000003069
Journal or Publication Title:	Anesthesiology
Volume:	132
Number:	3
Page Range:	S. 525 - 535
Date:	2020
Publisher:	LIPPINCOTT WILLIAMS & WILKINS
Place of Publication:	PHILADELPHIA
ISSN:	1528-1175
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ANTI-D Multiple languages Anesthesiology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/34212