Universität zu Köln

Santesso, Nancy, Glenton, Claire, Dahm, Philipp, Garner, Paul ORCID: 0000-0002-0607-6941, Akl, Elie A., Alper, Brian, Brignardello-Petersen, Romina, Carrasco-Labra, Alonso ORCID: 0000-0003-3546-3526, De Beer, Hans, Hultcrantz, Monica, Kuijpers, Ton, Meerpohl, Joerg, Morgan, Rebecca ORCID: 0000-0002-1012-4897, Mustafa, Reem, Skoetz, Nicole, Sultan, Shahnaz, Wiysonge, Charles ORCID: 0000-0002-1273-4779, Guyatt, Gordon and Schunemann, Holger J. (2020). GRADE guidelines 26: informative statements to communicate the findings of systematic reviews of interventions. J. Clin. Epidemiol., 119. S. 126 - 136. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1878-5921

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Abstract

Objectives: Clear communication of systematic review findings will help readers and decision makers. We built on previous work to develop an approach that improves the clarity of statements to convey findings and that draws on Grading of Recommendations Assessment, Development and Evaluation (GRADE). Study Design and Setting: We conducted workshops including 80 attendants and a survey of 110 producers and users of systematic reviews. We calculated acceptability of statements and revised the wording of those that were unacceptable to >= 40% of participants. Results: Most participants agreed statements should be based on size of effect and certainty of evidence. Statements for low, moderate and high certainty evidence were acceptable to >60%. Key guidance, for example, includes statements for high, moderate and low certainty for a large effect on intervention x as: x results in a large reduction...; x likely results in a large reduction...; x may result in a large reduction..., respectively. Conclusions: Producers and users of systematic reviews found statements to communicate findings combining size and certainty of an effect acceptable. This article provides GRADE guidance and a wording template to formulate statements in systematic reviews and other decision tools. (C) 2019 The Authors. Published by Elsevier Inc.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Santesso, Nancy UNSPECIFIED UNSPECIFIED UNSPECIFIED Glenton, Claire UNSPECIFIED UNSPECIFIED UNSPECIFIED Dahm, Philipp UNSPECIFIED UNSPECIFIED UNSPECIFIED Garner, Paul UNSPECIFIED orcid.org/0000-0002-0607-6941 UNSPECIFIED Akl, Elie A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Alper, Brian UNSPECIFIED UNSPECIFIED UNSPECIFIED Brignardello-Petersen, Romina UNSPECIFIED UNSPECIFIED UNSPECIFIED Carrasco-Labra, Alonso UNSPECIFIED orcid.org/0000-0003-3546-3526 UNSPECIFIED De Beer, Hans UNSPECIFIED UNSPECIFIED UNSPECIFIED Hultcrantz, Monica UNSPECIFIED UNSPECIFIED UNSPECIFIED Kuijpers, Ton UNSPECIFIED UNSPECIFIED UNSPECIFIED Meerpohl, Joerg UNSPECIFIED UNSPECIFIED UNSPECIFIED Morgan, Rebecca UNSPECIFIED orcid.org/0000-0002-1012-4897 UNSPECIFIED Mustafa, Reem UNSPECIFIED UNSPECIFIED UNSPECIFIED Skoetz, Nicole UNSPECIFIED UNSPECIFIED UNSPECIFIED Sultan, Shahnaz UNSPECIFIED UNSPECIFIED UNSPECIFIED Wiysonge, Charles UNSPECIFIED orcid.org/0000-0002-1273-4779 UNSPECIFIED Guyatt, Gordon UNSPECIFIED UNSPECIFIED UNSPECIFIED Schunemann, Holger J. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-342834
DOI:	10.1016/j.jclinepi.2019.10.014
Journal or Publication Title:	J. Clin. Epidemiol.
Volume:	119
Page Range:	S. 126 - 136
Date:	2020
Publisher:	ELSEVIER SCIENCE INC
Place of Publication:	NEW YORK
ISSN:	1878-5921
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language DECISION ETD FRAMEWORKS; FINDINGS TABLES; QUALITY; CONFIDENCE; CERTAINTY Multiple languages Health Care Sciences & Services; Public, Environmental & Occupational Health Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/34283