Universität zu Köln

Balode, Darta, Belajeva, Ludmila, Ruesseler, Vanessa, Quaas, Alexander and Lejniece, Sandra (2020). Diagnostic Challenges and Treatment Options for Cutaneous T Cell Pseudolymphoma: A Case Study with Rituximab Treatment. Am. J. Case Rep., 21. MELVILLE: INT SCIENTIFIC INFORMATION, INC. ISSN 1941-5923

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Abstract

Objective: Rare disease Background: Pseudolymphoma is a rare disorder that can mimic lymphoma both clinically and histologically. It usually affects middle-aged females. Since pseudolymphoma is a rare disorder not only is diagnosing the condition difficult, but there is also a lack of standardized treatment guidelines. In the literature, anti-CD20 monoclonal antibody rituximab is described as an effective treatment option. Case Report: 46-year-old female fell ill suddenly with swelling and enlargement of her chin. Multiple skin biopsies were done, which were re-evaluated multiple times as well. Each ended with a new diagnosis for the patient. Finally, in the last revision of biopsy material, pseudolymphoma was confirmed. The patient received multiple courses of corticosteroid treatments - locally and systemically - without long lasting effect. After diagnosis of pseudolymphoma, the patient was started on intravenous rituximab and this treatment was effective. Conclusion: Cutaneous pseudolymphoma is a diagnostic challenge. Rituximab is a treatment option for refractory pseudolymphoma. Since there are no treatment guidelines for pseudolymphoma, more clinical studies are needed to establish best treatment options for these patients. Therefore, each reported clinical case is important.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Balode, Darta UNSPECIFIED UNSPECIFIED UNSPECIFIED Belajeva, Ludmila UNSPECIFIED UNSPECIFIED UNSPECIFIED Ruesseler, Vanessa UNSPECIFIED UNSPECIFIED UNSPECIFIED Quaas, Alexander UNSPECIFIED UNSPECIFIED UNSPECIFIED Lejniece, Sandra UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-349017
DOI:	10.12659/AJCR.919616
Journal or Publication Title:	Am. J. Case Rep.
Volume:	21
Date:	2020
Publisher:	INT SCIENTIFIC INFORMATION, INC
Place of Publication:	MELVILLE
ISSN:	1941-5923
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language LYMPHOID HYPERPLASIA Multiple languages Medicine, General & Internal Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/34901