Universität zu Köln

Suchorska, Bogdana and Ruge, Maximilian I. (2015). Deep Brain Stimulation: Current Applications and Future Prospects. Discov. Med., 20 (112). S. 365 - 374. TIMONIUM: DISCOVERY MEDICINE. ISSN 1944-7930

Full text not available from this repository.

Abstract

Deep Brain Stimulation (DBS) has proven to be an effective and minimally invasive surgical treatment for a variety of neurological and psychiatric diseases such as Parkinson's Disease, essential tremor, dystonia, Tourette's Syndrome and depression. In contrast to early surgical lesioning procedures, DBS has a considerably lower side-effect rate and is usually reversible. Common targets include nuclei involved in the basal ganglia circuitry as well as its efferent and afferent pathways such as the subthalamic nucleus (STN), the globus pallidus internus (GPi) or the ventral striatal region. Despite the increasing application of DBS, the exact mechanism of action is still matter of debates. Current trials focus on establishing alternative targets, exploring new indications as well as on capturing cortical responses during DBS in order to improve individual stimulation parameters.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Suchorska, Bogdana UNSPECIFIED UNSPECIFIED UNSPECIFIED Ruge, Maximilian I. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-384385
Journal or Publication Title:	Discov. Med.
Volume:	20
Number:	112
Page Range:	S. 365 - 374
Date:	2015
Publisher:	DISCOVERY MEDICINE
Place of Publication:	TIMONIUM
ISSN:	1944-7930
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language SUBTHALAMIC NUCLEUS STIMULATION; BASAL GANGLIA; THALAMIC-STIMULATION; PARKINSONS-DISEASE; TOURETTE-SYNDROME; ESSENTIAL TREMOR; GLOBUS-PALLIDUS; MOVEMENT-DISORDERS; NEURONAL-ACTIVITY; VENTRAL STRIATUM Multiple languages Medicine, Research & Experimental Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/38438