Universität zu Köln

Nawka, Tadeus, Sittel, Christian, Arens, Christoph ORCID: 0000-0001-8072-1438, Lang-Roth, Ruth, Wittekindt, Claus, Hagen, Rudolf, Mueller, Andreas H. ORCID: 0000-0002-9820-5527, Nasr, Ahmed I., Guntinas-Lichius, Orlando ORCID: 0000-0001-9671-0784, Friedrich, Gerhard and Gugatschka, Markus ORCID: 0000-0001-8091-8812 (2015). Voice and Respiratory Outcomes After Permanent Transoral Surgery of Bilateral Vocal Fold Paralysis. Laryngoscope, 125 (12). S. 2749 - 2756. HOBOKEN: WILEY-BLACKWELL. ISSN 1531-4995

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Abstract

Objectives/Hypothesis: Bilateral vocal fold paralysis (BVFP) is a rare but life-threatening condition mostly caused by iatrogenic damage to the peripheral recurrent laryngeal nerve. Endoscopic enlargement techniques have been the standard treatment for decades. However, prospective studies using internationally accepted phoniatric and respiratory evaluation guidelines are rare. Study Design: Prospective observational multicenter study. Methods: Twelve clinical centers screened 61 patients, of whom 36 were eligible according to the study protocol. Subjects were assessed with specific phoniatric and respiratory tests preoperatively and at 1 and 6 months postoperatively. Results: Important respiratory parameters improved significantly 6 months postoperatively (peak expiratory and expiratory flow), confirming that a glottal enlargement effectively reduced the obstruction. Objective parameters dealing with voice quality worsened significantly (maximum phonation time, voice range profile, hoarseness), whereas subjective voice assessment (VHI-12) did not change significantly. Conclusion: Endoscopic glottal enlargement is an effective method for relieving symptoms of dyspnea due to BVFP. Postoperatively, voice quality objectively worsened; however, this was not perceived by the patients themselves. Laryngostroboscopic findings did not correlate strongly with voice and respiratory outcomes.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Nawka, Tadeus UNSPECIFIED UNSPECIFIED UNSPECIFIED Sittel, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Arens, Christoph UNSPECIFIED orcid.org/0000-0001-8072-1438 UNSPECIFIED Lang-Roth, Ruth UNSPECIFIED UNSPECIFIED UNSPECIFIED Wittekindt, Claus UNSPECIFIED UNSPECIFIED UNSPECIFIED Hagen, Rudolf UNSPECIFIED UNSPECIFIED UNSPECIFIED Mueller, Andreas H. UNSPECIFIED orcid.org/0000-0002-9820-5527 UNSPECIFIED Nasr, Ahmed I. UNSPECIFIED UNSPECIFIED UNSPECIFIED Guntinas-Lichius, Orlando UNSPECIFIED orcid.org/0000-0001-9671-0784 UNSPECIFIED Friedrich, Gerhard UNSPECIFIED UNSPECIFIED UNSPECIFIED Gugatschka, Markus UNSPECIFIED orcid.org/0000-0001-8091-8812 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-385099
DOI:	10.1002/lary.25415
Journal or Publication Title:	Laryngoscope
Volume:	125
Number:	12
Page Range:	S. 2749 - 2756
Date:	2015
Publisher:	WILEY-BLACKWELL
Place of Publication:	HOBOKEN
ISSN:	1531-4995
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language LARYNGOLOGICAL SOCIETY ELS; CORD PARALYSIS; TOTAL ARYTENOIDECTOMY; TRANSVERSE CORDOTOMY; LASER; MULTICENTER; MANAGEMENT; CORDECTOMY; PROTOCOL; TRIAL Multiple languages Medicine, Research & Experimental; Otorhinolaryngology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/38509