Universität zu Köln

Santelmann, Hanno, Franklin, Jeremy ORCID: 0000-0003-1536-0925, Busshoff, Jana and Baethge, Christopher (2015). Test-retest reliability of schizoaffective disorder compared with schizophrenia, bipolar disorder, and unipolar depressiona systematic review and meta-analysis. Bipolar Disord., 17 (7). S. 753 - 769. HOBOKEN: WILEY. ISSN 1399-5618

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Abstract

ObjectivesSchizoaffective disorder is a frequent diagnosis, and its reliability is subject to ongoing discussion. We compared the diagnostic reliability of schizoaffective disorder with its main differential diagnoses. MethodsWe systematically searched Medline, Embase, and PsycInfo for all studies on the test-retest reliability of the diagnosis of schizoaffective disorder as compared with schizophrenia, bipolar disorder, and unipolar depression. We used meta-analytic methods to describe and compare Cohen's kappa as well as positive and negative agreement. In addition, multiple pre-specified and post hoc subgroup and sensitivity analyses were carried out. ResultsOut of 4,415 studies screened, 49 studies were included. Test-retest reliability of schizoaffective disorder was consistently lower than that of schizophrenia (in 39 out of 42 studies), bipolar disorder (27/33), and unipolar depression (29/35). The mean difference in kappa between schizoaffective disorder and the other diagnoses was approximately 0.2, and mean Cohen's kappa for schizoaffective disorder was 0.50 (95% confidence interval: 0.40-0.59). While findings were unequivocal and homogeneous for schizoaffective disorder's diagnostic reliability relative to its three main differential diagnoses (dichotomous: smaller versus larger), heterogeneity was substantial for continuous measures, even after subgroup and sensitivity analyses. ConclusionsIn clinical practice and research, schizoaffective disorder's comparatively low diagnostic reliability should lead to increased efforts to correctly diagnose the disorder.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Santelmann, Hanno UNSPECIFIED UNSPECIFIED UNSPECIFIED Franklin, Jeremy UNSPECIFIED orcid.org/0000-0003-1536-0925 UNSPECIFIED Busshoff, Jana UNSPECIFIED UNSPECIFIED UNSPECIFIED Baethge, Christopher UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-388183
DOI:	10.1111/bdi.12340
Journal or Publication Title:	Bipolar Disord.
Volume:	17
Number:	7
Page Range:	S. 753 - 769
Date:	2015
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1399-5618
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language PROJECT 2-YEAR STABILITY; GENETIC-STUDIES DIGS; DIAGNOSTIC STABILITY; FOLLOW-UP; PSYCHOTIC DISORDER; 1ST-EPISODE PSYCHOSIS; PSYCHIATRIC-DIAGNOSIS; FUNCTIONAL PSYCHOSES; TREATMENT INITIATION; CLINICAL-DIAGNOSIS Multiple languages Clinical Neurology; Neurosciences; Psychiatry Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/38818