Universität zu Köln

Roehr, S., Luck, T., Bickel, H., Brettschneider, C., Ernst, A., Fuchs, A., Heser, K., Koenig, H. H., Jessen, F., Lange, C., Moesch, E., Pentzek, M., Steinmann, S., Weyerer, S., Werle, J., Wiese, B., Scherer, M., Maier, W. and Riedel-Heller, S. G. (2015). Mortality in incident dementia - results from the German Study on Aging, Cognition, and Dementia in Primary Care Patients. Acta Psychiatr. Scand., 132 (4). S. 257 - 270. HOBOKEN: WILEY. ISSN 1600-0447

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Abstract

Objective: Dementia is known to increase mortality, but the relative loss of life years and contributing factors are not well established. Thus, we aimed to investigate mortality in incident dementia from disease onset. Method: Data were derived from the prospective longitudinal German AgeCoDe study. We used proportional hazards models to assess the impact of sociodemographic and health characteristics on mortality after dementia onset, Kaplan-Meier method for median survival times. Results: Of 3214 subjects at risk, 523 (16.3%) developed incident dementia during a 9-year follow-up period. Median survival time after onset was 3.2 years (95% CI = 2.8-3.7) at a mean age of 85.0 (SD = 4.0) years (>= 2.6 life years lost compared with the general German population). Survival was shorter in older age, males other dementias than Alzheimer's, and in the absence of subjective memory complaints (SMC). Conclusion: Our findings emphasize that dementia substantially shortens life expectancy. Future studies should further investigate the potential impact of SMC on mortality in dementia.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Roehr, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Luck, T. UNSPECIFIED UNSPECIFIED UNSPECIFIED Bickel, H. UNSPECIFIED UNSPECIFIED UNSPECIFIED Brettschneider, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Ernst, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Fuchs, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Heser, K. UNSPECIFIED UNSPECIFIED UNSPECIFIED Koenig, H. H. UNSPECIFIED UNSPECIFIED UNSPECIFIED Jessen, F. UNSPECIFIED UNSPECIFIED UNSPECIFIED Lange, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Moesch, E. UNSPECIFIED UNSPECIFIED UNSPECIFIED Pentzek, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Steinmann, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Weyerer, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Werle, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Wiese, B. UNSPECIFIED UNSPECIFIED UNSPECIFIED Scherer, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Maier, W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Riedel-Heller, S. G. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-391807
DOI:	10.1111/acps.12454
Journal or Publication Title:	Acta Psychiatr. Scand.
Volume:	132
Number:	4
Page Range:	S. 257 - 270
Date:	2015
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1600-0447
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ALZHEIMERS-DISEASE; VASCULAR DEMENTIA; FOLLOW-UP; MEMORY COMPLAINTS; SURVIVAL; POPULATION; PREDICTORS; DEATH; DIAGNOSIS; ASSOCIATION Multiple languages Psychiatry Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/39180