Universität zu Köln

Benz, M. R. and Kemper, M. J. (2015). Nephrotic syndrome in childhood. Mon.schr. Kinderheilkd., 163 (4). S. 310 - 322. NEW YORK: SPRINGER. ISSN 1433-0474

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Abstract

Despite being an orphan disease, idiopathic nephrotic syndrome in children is the most frequent glomerular disease in this age group. Nephrotic syndrome is characterized by severe proteinuria and hypoalbuminemia. Edema is mostly present, especially at initial presentation. Nephrotic syndrome in children is a heterogeneous disease with respect to age of onset, etiology, histology and response to the standard treatment with glucocorticoids. This diversity strongly influences the diagnostic approach and treatment. As the prognosis of steroid-sensitive nephrotic syndrome with respect to renal function is generally good, not only the efficacy but also the toxicity of different treatment regimens should be kept in mind when planning individualized treatment.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Benz, M. R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Kemper, M. J. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-408377
DOI:	10.1007/s00112-014-3224-4
Journal or Publication Title:	Mon.schr. Kinderheilkd.
Volume:	163
Number:	4
Page Range:	S. 310 - 322
Date:	2015
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1433-0474
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language MYCOPHENOLATE-MOFETIL; PREDNISOLONE THERAPY; CYCLOSPORINE-A; ONSET; MULTICENTER; CHILDREN; CYCLOPHOSPHAMIDE; MANAGEMENT; INFECTION; RITUXIMAB Multiple languages Pediatrics Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/40837