Universität zu Köln

Schmidt, Christian, Fingerle-Rowson, Guenter, Boehme, Angelika, Brendel, Kurt, Fischer, Richard, Gonnermann, Michael, Hoehler, Thomas, Kegel, Thomas, Kellermann, Lenka, Nusch, Arndt, Poenisch, Wolfram, Wendtner, Clemens and Dreyling, Martin (2015). Changes in the diagnosis and treatment of patients with low grade lymphoma in Germany: years 2006-2009. Leuk. Lymphoma, 56 (3). S. 694 - 703. ABINGDON: TAYLOR & FRANCIS LTD. ISSN 1029-2403

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Abstract

Today's treatment options for indolent lymphoma and chronic lymphocytic leukemia (CLL) range from watch & wait, immunochemotherapy up to allogeneic transplantation. We describe changes in the diagnosis and treatment of indolent lymphoma and CLL in Germany between 2006 and 2009. Two nation-wide surveys in the fourth quarter of 2006 and 2009 included patients with indolent lymphoma and CLL. Data from 576 patients from 46 centers in Q4/2006 were compared with data from 521 patients from 57 centers in Q4/2009. The subpopulation of patients >= 70 years of age and the number of patients with comorbidities increased from 39% to 55% and 47% to 55%, respectively. Both in indolent lymphoma and CLL, Rituximab and R-based immunochemotherapy (50.6% vs. 64.4%) as well as bendamustine (4.8% vs. 24%) were much more frequently applied. In contrast, high dose chemotherapy consolidation was almost abandoned in first line treatment. Supportive care is given more frequently, with exception of erythropoietin and immunoglobulins. Our national survey confirmed that scientific results were rapidly transferred into clinical care of indolent lymphoma.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Schmidt, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Fingerle-Rowson, Guenter UNSPECIFIED UNSPECIFIED UNSPECIFIED Boehme, Angelika UNSPECIFIED UNSPECIFIED UNSPECIFIED Brendel, Kurt UNSPECIFIED UNSPECIFIED UNSPECIFIED Fischer, Richard UNSPECIFIED UNSPECIFIED UNSPECIFIED Gonnermann, Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED Hoehler, Thomas UNSPECIFIED UNSPECIFIED UNSPECIFIED Kegel, Thomas UNSPECIFIED UNSPECIFIED UNSPECIFIED Kellermann, Lenka UNSPECIFIED UNSPECIFIED UNSPECIFIED Nusch, Arndt UNSPECIFIED UNSPECIFIED UNSPECIFIED Poenisch, Wolfram UNSPECIFIED UNSPECIFIED UNSPECIFIED Wendtner, Clemens UNSPECIFIED UNSPECIFIED UNSPECIFIED Dreyling, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-410862
DOI:	10.3109/10428194.2014.928935
Journal or Publication Title:	Leuk. Lymphoma
Volume:	56
Number:	3
Page Range:	S. 694 - 703
Date:	2015
Publisher:	TAYLOR & FRANCIS LTD
Place of Publication:	ABINGDON
ISSN:	1029-2403
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CHRONIC LYMPHOCYTIC-LEUKEMIA; ADVANCED FOLLICULAR LYMPHOMA; STEM-CELL TRANSPLANTATION; RITUXIMAB MAINTENANCE; UNTREATED PATIENTS; CHEMOTHERAPY; SURVIVAL; THERAPY; CYCLOPHOSPHAMIDE; GUIDELINES Multiple languages Oncology; Hematology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/41086