Universität zu Köln

Rosenkranz, Stephan (2015). Pulmonary hypertension 2015: current definitions, terminology, and novel treatment options. Clin. Res. Cardiol., 104 (3). S. 197 - 208. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1861-0692

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Abstract

Pulmonary hypertension (PH) is a common phenomenon that may occur as a consequence of various diseases (e.g., heart failure, chronic lung diseases, and pulmonary embolism), as a distinct disease of the small pulmonary arterioles, or a combination of both. Independently from the origin, PH has important impact on patientA ' s symptoms and life expectancy. The establishment of an exact diagnosis and classification, as well as the understanding of the hemodynamic interrelations, provides the basis for often challenging treatment decisions. Recently, the 5th World Symposium on PH took place in Nice, France, where important standards and definitions were specified. Furthermore, the results of recent phase III trials have led to the approval of new targeted therapies. The most relevant developments including the rating of novel treatment options are summarized in this article.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Rosenkranz, Stephan UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-411265
DOI:	10.1007/s00392-014-0765-4
Journal or Publication Title:	Clin. Res. Cardiol.
Volume:	104
Number:	3
Page Range:	S. 197 - 208
Date:	2015
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1861-0692
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language PRESERVED EJECTION FRACTION; DISEASE UPDATED RECOMMENDATIONS; ARTERIAL-HYPERTENSION; HEART-FAILURE; IRON-DEFICIENCY; PHOSPHODIESTERASE-5 INHIBITION; TREATMENT ALGORITHM; EXERCISE CAPACITY; PROGNOSTIC VALUE; RIOCIGUAT Multiple languages Cardiac & Cardiovascular Systems Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/41126