Universität zu Köln

Gnoth, Christian, Markhinin, Vitaly, Maxrath, Beatrice, Skonieczny, Therese, Friol, Kerstin, Roos, Judith, Rahimi, Gohar and Godehardt, Erhard (2015). Impact of sperm cell source on the results of intracytoplasmic sperm injection. Arch. Gynecol. Obstet., 291 (3). S. 663 - 670. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0711

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Abstract

There is an ongoing debate whether the source of sperm cells, the etiology or the extent of male factor infertility has influence on the outcome of ICSI cycles. The results of intracytoplasmic sperm injection (ICSI) according to the source of spermatozoa in patients with severe male factor infertility were compared in a retrospective study: 249 couples underwent a total of 337 fresh ICSI cycles with the use of fresh motile testicular or fresh motile ejaculated spermatozoa. For all variables, there were no statistically significant differences in the ICSI results between both groups. Fertilization rates were 46.8 % for testicular and 47.6 % for ejaculated spermatozoa. Live birth rates per embryo transfer were 20.4 % using testicular spermatozoa and 22.8 % using ejaculated spermatozoa. Neither the source of spermatozoa nor the etiology of severe male infertility has relevant impact on the results of ICSI cycles as long as fresh motile, morphologically normal spermatozoa are used. Therefore, in case of cryptozoospermia, we recommend to preferentially use ejaculated spermatozoa to prevent those men from an unnecessary testicular biopsy avoiding risks and costs implied.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Gnoth, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Markhinin, Vitaly UNSPECIFIED UNSPECIFIED UNSPECIFIED Maxrath, Beatrice UNSPECIFIED UNSPECIFIED UNSPECIFIED Skonieczny, Therese UNSPECIFIED UNSPECIFIED UNSPECIFIED Friol, Kerstin UNSPECIFIED UNSPECIFIED UNSPECIFIED Roos, Judith UNSPECIFIED UNSPECIFIED UNSPECIFIED Rahimi, Gohar UNSPECIFIED UNSPECIFIED UNSPECIFIED Godehardt, Erhard UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-411360
DOI:	10.1007/s00404-014-3448-5
Journal or Publication Title:	Arch. Gynecol. Obstet.
Volume:	291
Number:	3
Page Range:	S. 663 - 670
Date:	2015
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1432-0711
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language IN-VITRO FERTILIZATION; TESTICULAR SPERMATOZOA; OXIDATIVE STRESS; MALE-INFERTILITY; ICSI; MEN; AZOOSPERMIA; EJACULATE; QUALITY Multiple languages Obstetrics & Gynecology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/41136