Universität zu Köln

Fatullayev, Javid, Samak, Mostafa, Sabashnikov, Anton ORCID: 0000-0002-6289-1035, Zeriouh, Mohamed, Rahmanian, Parwis B. ORCID: 0000-0002-3978-9251, Choi, Yeong-Hoon, Schmack, Bastian, Kallenbach, Klaus, Ruhparwar, Arjang, Eghbalzadeh, Kaveh, Dohmen, Pascal M., Karck, Matthias, Wippermann, Jens, Wahlers, Thorsten, Popov, Aron-Frederik ORCID: 0000-0003-4226-3004, Simon, Andre R. and Weymann, Alexander (2015). Continuous-Flow Left Ventricular Assist Device Thrombosis: A Danger Foreseen is a Danger Avoided. Med. Sci. Monit. Basic Res., 21. S. 141 - 145. MELVILLE: INT SCIENTIFIC INFORMATION, INC. ISSN 2325-4394

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Abstract

Left ventricular assist devices (LVAD) are an increasingly implemented therapeutic intervention for patients with end-stage heart failure. A growing body of evidence, however, has shown an elevated risk of device thrombosis, a major complication jeopardizing the patient's post-implantation survival. To date, multiple causative factors for LVAD thrombosis have been identified, such as internal shear stress, device material, infection, and inadequate anticoagulation. Understanding the mechanisms leading to LVAD thrombosis will not only enable device optimization, but also allow for better patient handling, hence improving post-implantation outcome. In this review we highlight the most commonly identified factors leading to LVAD thrombosis and discuss their mechanisms.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Fatullayev, Javid UNSPECIFIED UNSPECIFIED UNSPECIFIED Samak, Mostafa UNSPECIFIED UNSPECIFIED UNSPECIFIED Sabashnikov, Anton UNSPECIFIED orcid.org/0000-0002-6289-1035 UNSPECIFIED Zeriouh, Mohamed UNSPECIFIED UNSPECIFIED UNSPECIFIED Rahmanian, Parwis B. UNSPECIFIED orcid.org/0000-0002-3978-9251 UNSPECIFIED Choi, Yeong-Hoon UNSPECIFIED UNSPECIFIED UNSPECIFIED Schmack, Bastian UNSPECIFIED UNSPECIFIED UNSPECIFIED Kallenbach, Klaus UNSPECIFIED UNSPECIFIED UNSPECIFIED Ruhparwar, Arjang UNSPECIFIED UNSPECIFIED UNSPECIFIED Eghbalzadeh, Kaveh UNSPECIFIED UNSPECIFIED UNSPECIFIED Dohmen, Pascal M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Karck, Matthias UNSPECIFIED UNSPECIFIED UNSPECIFIED Wippermann, Jens UNSPECIFIED UNSPECIFIED UNSPECIFIED Wahlers, Thorsten UNSPECIFIED UNSPECIFIED UNSPECIFIED Popov, Aron-Frederik UNSPECIFIED orcid.org/0000-0003-4226-3004 UNSPECIFIED Simon, Andre R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Weymann, Alexander UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-419374
DOI:	10.12659/MSMBR.894840
Journal or Publication Title:	Med. Sci. Monit. Basic Res.
Volume:	21
Page Range:	S. 141 - 145
Date:	2015
Publisher:	INT SCIENTIFIC INFORMATION, INC
Place of Publication:	MELVILLE
ISSN:	2325-4394
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language HEART-FAILURE; COAGULATION; MANAGEMENT; SYSTEM; STATE Multiple languages Medicine, Research & Experimental Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/41937