Universität zu Köln

Mehler, Katrin, Nowak, Mareike, Oberthuer, Andre, Hahn, Moritz, Roth, Bernhard and Kribs, Angela (2014). Blood sampling via a peripheral artery catheter decreases cerebral oxygenation index in very low-birthweight infants. Acta Paediatr., 103 (12). S. 1227 - 1233. HOBOKEN: WILEY. ISSN 1651-2227

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Abstract

AimThis study evaluated the impact of blood sampling via peripheral arterial catheters on cerebral oxygenation and blood volume as a function of blood sampling velocity. MethodsNear-infrared spectroscopy was applied to 20 very low-birthweight infants during peripheral arterial blood sampling. Changes in cerebral oxygenated, deoxygenated and total haemoglobin, cerebral blood volume and cerebral oxygenation index were recorded. Heart rate and oxygen saturation were measured continuously. To assess the impact of blood sampling velocity, both fast 40-sec and slow 70-sec sampling procedures were performed in a crossover study design, in which the order of sampling velocities was randomised for each patient. ResultsBoth fast and slow blood sampling procedures resulted in a significant decrease in cerebral oxygenation index (fast, p=0.002, slow, p=0.008), and an increase in mean heart rate (both p=0.02) and mean blood pressure (p=0.02 and 0.04). Oxygenated and total haemoglobin and cerebral blood volume only decreased significantly after slow blood sampling (p<0.001). ConclusionBlood sampling from peripheral arterial catheters leads to significant fluctuations in cerebral oxygenation independent of the sampling velocity. Changes are comparable to those reported from umbilical blood sampling. We advise that blood sampling should be restricted as much as possible.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Mehler, Katrin UNSPECIFIED UNSPECIFIED UNSPECIFIED Nowak, Mareike UNSPECIFIED UNSPECIFIED UNSPECIFIED Oberthuer, Andre UNSPECIFIED UNSPECIFIED UNSPECIFIED Hahn, Moritz UNSPECIFIED UNSPECIFIED UNSPECIFIED Roth, Bernhard UNSPECIFIED UNSPECIFIED UNSPECIFIED Kribs, Angela UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-421925
DOI:	10.1111/apa.12805
Journal or Publication Title:	Acta Paediatr.
Volume:	103
Number:	12
Page Range:	S. 1227 - 1233
Date:	2014
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1651-2227
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language SICK NEWBORN-INFANTS; VOLUME; AUTOREGULATION; FLOW; QUANTIFICATION; BABIES; IMPACT; BORN Multiple languages Pediatrics Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/42192