Pagliara, S., Dettmer, S. L., Misiunas, K., Lea, L., Tan, Y. and Keyser, U. F. (2014). Diffusion coefficients and particle transport in synthetic membrane channels. Eur. Phys. J.-Spec. Top., 223 (14). S. 3145 - 3164. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1951-6401

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Abstract

Diffusion in constrained geometries is paramount to transport across biological membranes and in mesoporous materials. Although the transported species vary from system to system, the underlying physical mechanisms are universal. However, there is an imbalance between theory and quantitative experimental model systems. We have recently introduced a new synthetic approach to mimic molecular diffusion based on colloidal particles, digital video microscopy, particle tracking, microfluidics and holographic optical tweezers. In this paper we report useful guidelines for the fabrication, handling and characterisation of the microfluidic chips and a study of diffusion coefficients, particle attempt and translocation rates through microfluidic channels with cross sections of different dimensions.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Pagliara, S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dettmer, S. L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Misiunas, K.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lea, L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tan, Y.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Keyser, U. F.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-422466
DOI: 10.1140/epjst/e2014-02324-6
Journal or Publication Title: Eur. Phys. J.-Spec. Top.
Volume: 223
Number: 14
Page Range: S. 3145 - 3164
Date: 2014
Publisher: SPRINGER HEIDELBERG
Place of Publication: HEIDELBERG
ISSN: 1951-6401
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
SINGLE-FILE DIFFUSION; SELECTIVE TRANSPORT; CRYSTAL-STRUCTURES; MASS-TRANSFER; MOLECULE; TRANSLOCATION; COLLOIDS; BINDING; CELLS; TIMEMultiple languages
Physics, MultidisciplinaryMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/42246

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