Universität zu Köln

Belz, D., Hunzelmann, N. and Moinzadeh, P. (2014). Digital ulcers in systemic scleroderma. Hautarzt, 65 (11). S. 944 - 949. NEW YORK: SPRINGER. ISSN 1432-1173

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Abstract

Digital ulcers (DU's) are one of the main symptoms of systemic scleroderma and occur in approximately 60 % of all scleroderma patients. Due to possible complications such as infections, gangrene or amputation, they require regular medical attention and a good wound treatment by doctors and nursing staff. A definition of DU's has not yet been established. In 2009 the European League Against Rheumatism (EULAR) published guidelines for the treatment of DU's. An improvement of the healing of active ulcers has been described with Iloprost. Bosentan significantly reduced the frequency of occurrence of new DU's. In some small studies PDE-5 inhibitors appear helpful. Further studies with other therapeutic approaches will follow in the next few years.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Belz, D. UNSPECIFIED UNSPECIFIED UNSPECIFIED Hunzelmann, N. UNSPECIFIED UNSPECIFIED UNSPECIFIED Moinzadeh, P. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-424226
DOI:	10.1007/s00105-014-3528-2
Journal or Publication Title:	Hautarzt
Volume:	65
Number:	11
Page Range:	S. 944 - 949
Date:	2014
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1432-1173
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language RAYNAUDS-PHENOMENON RESISTANT; DOUBLE-BLIND; NAILFOLD CAPILLAROSCOPY; VASCULAR-DISEASE; SCLEROSIS; THERAPY; SECONDARY; VASCULOPATHY; MULTICENTER; SILDENAFIL Multiple languages Dermatology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/42422