Universität zu Köln

Kuehn, Tilman, Kroke, Anja, Remer, Thomas, Schoenau, Eckhard and Buyken, Anette E. (2014). Is breastfeeding related to bone properties? A longitudinal analysis of associations between breastfeeding duration and pQCT parameters in children and adolescents. Matern. Child Nutr., 10 (4). S. 642 - 650. HOBOKEN: WILEY. ISSN 1740-8709

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Abstract

Nutritive and bioactive components of human milk could be involved in programming metabolic systems that affect bone growth throughout the life course. Bone properties in childhood and adolescence might differ, depending on breastfeeding duration. Thus, breastfeeding could be a relevant factor in the context of primary osteoporosis prevention. The prospective association between breastfeeding duration and bone properties was investigated using the data of 284 participants of the Dortmund Nutritional and Anthropometric Longitudinally Designed Study. Breastfeeding duration was assessed during infancy. Bone properties were measured by peripheral quantitative computed tomography (pQCT) at ages 5-23 years. Cortical volumetric bone mineral density, cortical bone mineral content, strength strain index, total cross-sectional area of the bone and cross-sectional area of the cortical bone were determined at the 65% site of the radius. Linear regression analyses were performed to check for differences in pQCT parameters of subjects who had not or shortly been breastfed (0-16 weeks) and subjects who had been breastfed for a long duration (17 weeks). Multivariable models adjusted for age, gender, forearm length, muscle cross-sectional area, body mass index standard deviation score (SDS), height SDS and socio-economic status did not yield associations between breastfeeding duration and pQCT parameters. These findings suggest neither protective nor adverse effects of prolonged breastfeeding on bone health in childhood and adolescence. Influences of early nutrition on bone growth might be overridden by current effects of mechanical loads on bone physiology.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Kuehn, Tilman UNSPECIFIED UNSPECIFIED UNSPECIFIED Kroke, Anja UNSPECIFIED UNSPECIFIED UNSPECIFIED Remer, Thomas UNSPECIFIED UNSPECIFIED UNSPECIFIED Schoenau, Eckhard UNSPECIFIED UNSPECIFIED UNSPECIFIED Buyken, Anette E. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-427418
DOI:	10.1111/j.1740-8709.2012.00443.x
Journal or Publication Title:	Matern. Child Nutr.
Volume:	10
Number:	4
Page Range:	S. 642 - 650
Date:	2014
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1740-8709
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language PRETERM INFANTS; BIRTH-WEIGHT; EARLY DIET; EARLY-LIFE; MASS; GROWTH; AGE; NUTRITION; HEALTH; MINERALIZATION Multiple languages Nutrition & Dietetics; Pediatrics Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/42741