Universität zu Köln

Wiebe, Jens, Franke, Jennifer, Lubos, Edith, Boekstegers, Peter, Schillinger, Wolfgang, Ouarrak, Taoufik, May, Andreas E., Eggebrecht, Holger, Kuck, Karl-Heinz, Baldus, Stephan, Senges, Jochen and Sievert, Horst (2014). Percutaneous Mitral Valve Repair With the MitraClip System According to the Predicted Risk by the Logistic EuroSCORE: Preliminary Results From the German Transcatheter Mitral Valve Interventions (TRAMI) Registry. Catheter. Cardiovasc. Interv., 84 (4). S. 591 - 599. HOBOKEN: WILEY. ISSN 1522-726X

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Abstract

Objective: To evaluate in-hospital and short-term outcomes of percutaneous mitral valve repair according to patients' logistic EuroSCORE (logEuroSCORE) in a multicenter registry Background: The logEuroSCORE is an established tool to predict the risk of mortality during cardiac surgery. In high-risk patients percutaneous mitral valve repair with the MitraClip system represents a less-invasive alternative Methods: Data from 1002 patients, who underwent percutaneous mitral valve repair with the MitraClip system, were analyzed in the German Transcatheter Mitral Valve Interventions (TRAMI) Registry. A logEuroSCORE (mortality risk in %) >= 20 was considered high risk Results: Of all patients, 557 (55.6%) had a logEuroSCORE >= 20. Implantation of the MitraClip was successful in 95.5 % (942/986) patients. Moderate residual mitral valve regurgitation was more often detected in patients with a logEuroSCORE >= 20 (23.8% vs. 17.1%, respectively, P < 0.05). In patients with a logEuroSCORE >= 20 the procedural complication rate was 8.9% (vs. 6.4, n.s.) and the in-hospital MACCE rate 4.9% (vs. 1.4% P < 0.01). The in-hospital mortality rate in patients with a logEuroSCORE >= 20 and logEuroSCORE < 20 was 4.3 and 1.1%, respectively (P <= 0.01) Conclusion: Percutaneous mitral valve repair with the MitraClip system is feasible in patients with a logEuroSCORE >= 20 with similar procedural results compared to patients with lower predicted risk. Although mortality was four times higher than in patients with logEuroSCORE < 20, mortality in high risk patients was lower than predicted. In those with a logEuroSCORE >= 20, moderate residual mitral valve regurgitation was more frequent. (C) 2014 Wiley Periodicals, Inc.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Wiebe, Jens UNSPECIFIED UNSPECIFIED UNSPECIFIED Franke, Jennifer UNSPECIFIED UNSPECIFIED UNSPECIFIED Lubos, Edith UNSPECIFIED UNSPECIFIED UNSPECIFIED Boekstegers, Peter UNSPECIFIED UNSPECIFIED UNSPECIFIED Schillinger, Wolfgang UNSPECIFIED UNSPECIFIED UNSPECIFIED Ouarrak, Taoufik UNSPECIFIED UNSPECIFIED UNSPECIFIED May, Andreas E. UNSPECIFIED UNSPECIFIED UNSPECIFIED Eggebrecht, Holger UNSPECIFIED UNSPECIFIED UNSPECIFIED Kuck, Karl-Heinz UNSPECIFIED UNSPECIFIED UNSPECIFIED Baldus, Stephan UNSPECIFIED UNSPECIFIED UNSPECIFIED Senges, Jochen UNSPECIFIED UNSPECIFIED UNSPECIFIED Sievert, Horst UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-427864
DOI:	10.1002/ccd.25493
Journal or Publication Title:	Catheter. Cardiovasc. Interv.
Volume:	84
Number:	4
Page Range:	S. 591 - 599
Date:	2014
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1522-726X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language LEARNING-CURVE; REGURGITATION; OUTCOMES; SURGERY; REPLACEMENT; THERAPY; LESSONS; SOCIETY Multiple languages Cardiac & Cardiovascular Systems Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/42786