Universität zu Köln

Stetefeld, Henning R., Lehmann, Helmar C., Fink, Gereon R. ORCID: 0000-0002-8230-1856 and Burghaus, Lothar (2014). Posterior Reversible Encephalopathy Syndrome and Stroke after Intravenous Immunoglobulin Treatment in Miller-Fisher Syndrome/Bickerstaff Brain Stem Encephalitis Overlap Syndrome. J. Stroke Cerebrovasc. Dis., 23 (9). S. E423 - 3. AMSTERDAM: ELSEVIER SCIENCE BV. ISSN 1532-8511

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Abstract

The association of a posterior reversible encephalopathy syndrome (PRES) without arterial hypertension with autoimmune-mediated inflammatory neuropathies such as Guillain-Barre syndrome (GBS) is a rare and poorly understood phenomenon. To date, PRES has been described as initial manifestation, coincidental finding, or adverse event subsequent to immunomodulatory treatment with intravenous immunoglobulin (IVIG) in cases of axonal and demyelinating GBS as well as in Miller-Fisher syndrome (MFS). We here report a case of MFS/Bickerstaff brain stem encephalitis (BBE)-overlap syndrome and nonhypertensive PRES that occurred in close temporal association with IVIG treatment and caused stroke. Immunoadsorption ameliorated the disease course. Our case supports the notion that in severe cases, immunoadsorption should be considered as first-line therapy instead of IVIG for rapid removal of IgG and thus to hasten recovery and improve functional outcome.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Stetefeld, Henning R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Lehmann, Helmar C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Fink, Gereon R. UNSPECIFIED orcid.org/0000-0002-8230-1856 UNSPECIFIED Burghaus, Lothar UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-428176
DOI:	10.1016/j.jstrokecerebrovasdis.2014.05.034
Journal or Publication Title:	J. Stroke Cerebrovasc. Dis.
Volume:	23
Number:	9
Page Range:	S. E423 - 3
Date:	2014
Publisher:	ELSEVIER SCIENCE BV
Place of Publication:	AMSTERDAM
ISSN:	1532-8511
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language GUILLAIN-BARRE-SYNDROME; PATIENT; MANIFESTATION Multiple languages Neurosciences; Peripheral Vascular Disease Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/42817