Universität zu Köln

Schaefer, Carola, Enning, Frank, Mueller, Juliane K., Bumb, J. Malte, Rohleder, Cathrin ORCID: 0000-0002-3559-1846, Odorfer, Thorsten M., Klosterkoetter, Joachim, Hellmich, Martin, Koethe, Dagmar, Schmahl, Christian ORCID: 0000-0003-0141-0821, Bohus, Martin and Leweke, F. Markus ORCID: 0000-0002-8163-195X (2014). Fatty acid ethanolamide levels are altered in borderline personality and complex posttraumatic stress disorders. Eur. Arch. Psych. Clin. Neurosci., 264 (5). S. 459 - 464. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1433-8491

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Abstract

Borderline personality (BPD) and complex posttraumatic stress disorders (PTSD) are both powerfully associated with the experience of interpersonal violence during childhood and adolescence. The disorders frequently co-occur and often result in pervasive problems in, e.g., emotion regulation and altered pain perception, where the endocannabinoid system is deeply involved. We hypothesize an endocannabinoid role in both disorders. We investigated serum levels of the endocannabinoids anandamide and 2-arachidonoylglycerol and related fatty acid ethanolamides (FAEs) in BPD, PTSD, and controls. Significant alterations were found for both endocannabinoids in BPD and for the FAE oleoylethanolamide in PTSD suggesting a respective link to both disorders.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Schaefer, Carola UNSPECIFIED UNSPECIFIED UNSPECIFIED Enning, Frank UNSPECIFIED UNSPECIFIED UNSPECIFIED Mueller, Juliane K. UNSPECIFIED UNSPECIFIED UNSPECIFIED Bumb, J. Malte UNSPECIFIED UNSPECIFIED UNSPECIFIED Rohleder, Cathrin UNSPECIFIED orcid.org/0000-0002-3559-1846 UNSPECIFIED Odorfer, Thorsten M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Klosterkoetter, Joachim UNSPECIFIED UNSPECIFIED UNSPECIFIED Hellmich, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED Koethe, Dagmar UNSPECIFIED UNSPECIFIED UNSPECIFIED Schmahl, Christian UNSPECIFIED orcid.org/0000-0003-0141-0821 UNSPECIFIED Bohus, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED Leweke, F. Markus UNSPECIFIED orcid.org/0000-0002-8163-195X UNSPECIFIED
URN:	urn:nbn:de:hbz:38-432834
DOI:	10.1007/s00406-013-0470-8
Journal or Publication Title:	Eur. Arch. Psych. Clin. Neurosci.
Volume:	264
Number:	5
Page Range:	S. 459 - 464
Date:	2014
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1433-8491
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language PSYCHOTIC SYMPTOMS; SYSTEM; SCHIZOPHRENIA; EXTINCTION Multiple languages Clinical Neurology; Psychiatry Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/43283