Universität zu Köln

Berlth, Felix ORCID: 0000-0002-3780-0728, Bollschweiler, Elfriede, Drebber, Uta, Hoelscher, Arnulf H. and Moenig, Stefan (2014). Pathohistological classification systems in gastric cancer: Diagnostic relevance and prognostic value. World J. Gastroenterol., 20 (19). S. 5679 - 5685. PLEASANTON: BAISHIDENG PUBLISHING GROUP INC. ISSN 2219-2840

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Abstract

Several pathohistological classification systems exist for the diagnosis of gastric cancer. Many studies have investigated the correlation between the pathohistological characteristics in gastric cancer and patient characteristics, disease specific criteria and overall outcome. It is still controversial as to which classification system imparts the most reliable information, and therefore, the choice of system may vary in clinical routine. In addition to the most common classification systems, such as the Lauren and the World Health Organization (WHO) classifications, other authors have tried to characterize and classify gastric cancer based on the microscopic morphology and in reference to the clinical outcome of the patients. In more than 50 years of systematic classification of the pathohistological characteristics of gastric cancer, there is no sole classification system that is consistently used worldwide in diagnostics and research. However, several national guidelines for the treatment of gastric cancer refer to the Lauren or the WHO classifications regarding therapeutic decision-making, which underlines the importance of a reliable classification system for gastric cancer. The latest results from gastric cancer studies indicate that it might be useful to integrate DNA-and RNA-based features of gastric cancer into the classification systems to establish prognostic relevance. This article reviews the diagnostic relevance and the prognostic value of different pathohistological classification systems in gastric cancer. (C) 2014 Baishideng Publishing Group Inc. All rights reserved.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Berlth, Felix UNSPECIFIED orcid.org/0000-0002-3780-0728 UNSPECIFIED Bollschweiler, Elfriede UNSPECIFIED UNSPECIFIED UNSPECIFIED Drebber, Uta UNSPECIFIED UNSPECIFIED UNSPECIFIED Hoelscher, Arnulf H. UNSPECIFIED UNSPECIFIED UNSPECIFIED Moenig, Stefan UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-437842
DOI:	10.3748/wjg.v20.i19.5679
Journal or Publication Title:	World J. Gastroenterol.
Volume:	20
Number:	19
Page Range:	S. 5679 - 5685
Date:	2014
Publisher:	BAISHIDENG PUBLISHING GROUP INC
Place of Publication:	PLEASANTON
ISSN:	2219-2840
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CLINICOPATHOLOGICAL CHARACTERISTICS; HISTOLOGICAL CLASSIFICATION; HISTOPATHOLOGICAL SUBTYPES; GOSEKI CLASSIFICATION; LAUREN CLASSIFICATION; MING CLASSIFICATION; SURGICAL-TREATMENT; INTESTINAL-TYPE; CARCINOMA; STOMACH Multiple languages Gastroenterology & Hepatology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/43784