Universität zu Köln

Steinke, Sabine I. B., Peitsch, Wiebke K., Ludwig, Alexander and Goebeler, Matthias (2013). Cost-of-Illness in Psoriasis: Comparing Inpatient and Outpatient Therapy. PLoS One, 8 (10). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1932-6203

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Abstract

Treatment modalities of chronic plaque psoriasis have dramatically changed over the past ten years with a still continuing shift from inpatient to outpatient treatment. This development is mainly caused by outpatient availability of highly efficient and relatively well-tolerated systemic treatments, in particular BioLogicals. In addition, inpatient treatment is time-and cost-intense, conflicting with the actual burst of health expenses and with patient preferences. Nevertheless, inpatient treatment with dithranol and UV light still is a major mainstay of psoriasis treatment in Germany. The current study aims at comparing the total costs of inpatient treatment and outpatient follow-up to mere outpatient therapy with different modalities (topical treatment, phototherapy, classic systemic therapy or BioLogicals) over a period of 12 months. To this end, a retrospective cost-of-illness study was conducted on 120 patients treated at the University Medical Centre Mannheim between 2005 and 2006. Inpatient therapy caused significantly higher direct medical, indirect and total annual costs than outpatient treatment (13,042 (sic) versus 2,984 (sic)). Its strong influence on cost levels was confirmed by regression analysis, with total costs rising by 104.3% in case of inpatient treatment. Patients receiving BioLogicals produced the overall highest costs, whereas outpatient treatment with classic systemic antipsoriatic medications was less cost-intense than other alternatives.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Steinke, Sabine I. B. UNSPECIFIED UNSPECIFIED UNSPECIFIED Peitsch, Wiebke K. UNSPECIFIED UNSPECIFIED UNSPECIFIED Ludwig, Alexander UNSPECIFIED UNSPECIFIED UNSPECIFIED Goebeler, Matthias UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-473882
DOI:	10.1371/journal.pone.0078152
Journal or Publication Title:	PLoS One
Volume:	8
Number:	10
Date:	2013
Publisher:	PUBLIC LIBRARY SCIENCE
Place of Publication:	SAN FRANCISCO
ISSN:	1932-6203
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language PLAQUE-TYPE PSORIASIS; HEALTH-CARE COSTS; PATIENT PREFERENCES; DISEASE SEVERITY; UNITED-STATES; MODERATE; LIFE; MULTICENTER; BIOLOGICS; GERMANY Multiple languages Multidisciplinary Sciences Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/47388