Universität zu Köln

Salokangas, R. K. R., Dingemans, P., Heinimaa, M., Svirskis, T., Luutonen, S., Hietala, J., Ruhrmann, S., Juckel, G., von Reventlow, H. Graf, Linszen, D., Birchwood, M., Patterson, P., Schultze-Lutter, F. and Klosterkoetter, J. (2013). Prediction of psychosis in clinical high-risk patients by the Schizotypal Personality Questionnaire. Results of the EPOS project. Eur. Psychiat., 28 (8). S. 469 - 476. ISSY-LES-MOULINEAUX: ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER. ISSN 1778-3585

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Abstract

Objective: Schizotypal features indicate proneness to psychosis in the general population. It is also possible that they increase transition to psychosis (TTP) among clinical high-risk patients (CHR). Our aim was to investigate whether schizotypal features predict TTP in CHR patients. Methods: In the EPOS (European Prediction of Psychosis Study) project, 245 young help-seeking CHR patients were prospectively followed for 18 months and their TTP was identified. At baseline, subjects were assessed with the Schizotypal Personality Questionnaire (SPQ). Associations between SPQ items and its subscales with the TTP were analysed in Cox regression analysis. Results: The SPQ subscales and items describing ideas of reference and lack of close interpersonal relationships were found to correlate significantly with TTP. The co-occurrence of these features doubled the risk of TTP. Conclusions: Presence of ideas of reference and lack of close interpersonal relations increase the risk of full-blown psychosis among CHR patients. This co-occurrence makes the risk of psychosis very high. (C) 2013 Elsevier Masson SAS. All rights reserved.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Salokangas, R. K. R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Dingemans, P. UNSPECIFIED UNSPECIFIED UNSPECIFIED Heinimaa, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Svirskis, T. UNSPECIFIED UNSPECIFIED UNSPECIFIED Luutonen, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Hietala, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Ruhrmann, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Juckel, G. UNSPECIFIED UNSPECIFIED UNSPECIFIED von Reventlow, H. Graf UNSPECIFIED UNSPECIFIED UNSPECIFIED Linszen, D. UNSPECIFIED UNSPECIFIED UNSPECIFIED Birchwood, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Patterson, P. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schultze-Lutter, F. UNSPECIFIED UNSPECIFIED UNSPECIFIED Klosterkoetter, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-474674
DOI:	10.1016/j.eurpsy.2013.01.001
Journal or Publication Title:	Eur. Psychiat.
Volume:	28
Number:	8
Page Range:	S. 469 - 476
Date:	2013
Publisher:	ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
Place of Publication:	ISSY-LES-MOULINEAUX
ISSN:	1778-3585
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language EDINBURGH HIGH-RISK; EPISODE PSYCHOSIS; PRODROMAL PHASE; MENTAL STATES; YOUNG-ADULTS; SCHIZOPHRENIA; ONSET; TRANSITION; ADOLESCENTS; DISORDERS Multiple languages Psychiatry Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/47467