Universität zu Köln

Schennach, R., Meyer, S., Seemueller, F., Jaeger, M., Schmauss, M., Laux, G., Pfeiffer, H., Naber, D., Schmidt, L. G., Gaebel, W., Klosterkoetter, J., Heuser, I., Maier, W., Lemke, M. R., Ruether, E., Klingberg, S., Gastpar, M., Moeller, H. -J. and Riedel, M. (2012). Insight in schizophrenia-course and predictors during the acute treatment phase of patients suffering from a schizophrenia spectrum disorder. Eur. Psychiat., 27 (8). S. 625 - 634. ISSY-LES-MOULINEAUX: ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER. ISSN 1778-3585

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Abstract

Background: To analyse insight of illness during the course of inpatient treatment, and to identify influencing factors and predictors of insight. Methods: Insight into illness was examined in 399 patients using the item G12 of the Positive and Negative Syndrome Scale (lack of insight and judgement). Ratings of the PANSS, HAMD, UKU, GAF, SOFAS, SWN-K and Kemp's compliance scale were performed and examined regarding their potential association with insight. The item G12 was kept as an ordinal variable to compare insight between subgroups of patients. Results: Almost 70% of patients had deficits in their insight into illness at admission. A significant improvement of impairments of insight during the treatment (p < 0.0001) was observed. At admission more severe positive and negative symptoms, worse functioning and worse adherence were significantly associated with poorer insight. Less depressive symptoms (p = 0.0004), less suicidality (p = 0.0218), suffering from multiple illness-episodes (p < 0.0001) and worse adherence (p = 0.0012) at admission were identified to be significant predictors of poor insight at discharge. Conclusion: The revealed predictors might function as treatment targets in order to improve insight and with it outcome of schizophrenia. (C) 2012 Elsevier Masson SAS. All rights reserved.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Schennach, R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Meyer, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Seemueller, F. UNSPECIFIED UNSPECIFIED UNSPECIFIED Jaeger, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schmauss, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Laux, G. UNSPECIFIED UNSPECIFIED UNSPECIFIED Pfeiffer, H. UNSPECIFIED UNSPECIFIED UNSPECIFIED Naber, D. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schmidt, L. G. UNSPECIFIED UNSPECIFIED UNSPECIFIED Gaebel, W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Klosterkoetter, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Heuser, I. UNSPECIFIED UNSPECIFIED UNSPECIFIED Maier, W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Lemke, M. R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Ruether, E. UNSPECIFIED UNSPECIFIED UNSPECIFIED Klingberg, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Gastpar, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Moeller, H. -J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Riedel, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-479841
DOI:	10.1016/j.eurpsy.2012.01.001
Journal or Publication Title:	Eur. Psychiat.
Volume:	27
Number:	8
Page Range:	S. 625 - 634
Date:	2012
Publisher:	ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
Place of Publication:	ISSY-LES-MOULINEAUX
ISSN:	1778-3585
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language EARLY PSYCHOSIS; ILLNESS; SYMPTOMS; DEPRESSION; UNAWARENESS; MEDICATION; ADHERENCE; AWARENESS Multiple languages Psychiatry Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/47984