Universität zu Köln

Regenfuss, Birgit, Bock, Felix and Cursiefen, Claus (2012). Corneal angiogenesis and lymphangiogenesis. Curr. Opin. Allergy Clin. Immunol., 12 (5). S. 548 - 555. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1528-4050

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Abstract

Purpose of review The purpose of the present review is to describe new antilymphangiogenic treatment strategies and recent findings on strain-dependency of corneal lymphangiogenesis and the interdependency between blood and lymphatic vessel growth. Recent findings Studies on mice have revealed that apart from haemangiogenesis, lymphangiogenesis can also differ markedly between several mouse strains under normal and inflammatory conditions. Although haemangiogenesis and lymphangiogenesis are closely interconnected in their spatial-temporal patterning, recent data suggest that they can also occur independently. Summary Understanding the coordinated regulation of blood and lymphatic vessel growth and genetic factors determining lymphangiogenesis in more detail could improve the development of specifically targeted antihaemangiogenic or antilymphangiogenic strategies.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Regenfuss, Birgit UNSPECIFIED UNSPECIFIED UNSPECIFIED Bock, Felix UNSPECIFIED UNSPECIFIED UNSPECIFIED Cursiefen, Claus UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-482116
DOI:	10.1097/ACI.0b013e328357b4a2
Journal or Publication Title:	Curr. Opin. Allergy Clin. Immunol.
Volume:	12
Number:	5
Page Range:	S. 548 - 555
Date:	2012
Publisher:	LIPPINCOTT WILLIAMS & WILKINS
Place of Publication:	PHILADELPHIA
ISSN:	1528-4050
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ENDOTHELIAL GROWTH-FACTOR; INSULIN-RECEPTOR SUBSTRATE-1; LYMPHATIC VESSEL GROWTH; GENETIC-HETEROGENEITY; MACULAR DEGENERATION; DIABETIC-RETINOPATHY; VEGF POLYMORPHISMS; GRAFT-SURVIVAL; SAFETY PROFILE; BREAST-CANCER Multiple languages Allergy; Immunology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/48211