Universität zu Köln

Stenner, M., Molls, C., Klussmann, J. -P. and Huettenbrink, K. -B. (2011). Prognosis of Surgically Treated Primary Parotid Gland Cancer - an Evaluation of 231 Cases. Laryngo-Rhino-Otol., 90 (11). S. 664 - 672. STUTTGART: GEORG THIEME VERLAG KG. ISSN 1438-8685

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Abstract

Objective: We present our results on the prognosis of parotid gland cancer with the help of a group of patients who were treated in a standardised manner and received a long term follow-up. Material and Methods: We retrospectively analysed the clinicopathological data of 231 patients with a surgically treated primary parotid gland cancer and calculated survival parameters. The mean follow-up time was 52 months. Results: The 5- and 10-year overall survival rate was 74.2 % and 66.9 %. 70 patients got a locoregional recurrence, 18.6% of those even after more than 5 years. Initial facial nerve palsy was a significant negative prognostic indicator for the disease-free survival. The most frequent histological subtypes could be divided into 3 prognostic groups with significant differences in the survival. The pathological tumour stage was a prognostic indicator for a worse overall and disease-free survival. The pT-stage, the pN-stage and the existence of distant metastases were independent prognostic factors. Conclusions: The group of patients is mainly characterised by the large size, the standardised therapy and the long follow-up time. We could show that the facial nerve palsy is a severe negative prognostic factor. For practical purpose, the classification into 3 histological subgroups seemed to be of great help. This should be considered in patient follow-up. Due to the amount of late recurrences, we propose a follow-up time longer than 5 years. We propose standardized surgery including total parotidectomy in combination with neck dissection.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Stenner, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Molls, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Klussmann, J. -P. UNSPECIFIED UNSPECIFIED UNSPECIFIED Huettenbrink, K. -B. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-485826
DOI:	10.1055/s-0031-1285924
Journal or Publication Title:	Laryngo-Rhino-Otol.
Volume:	90
Number:	11
Page Range:	S. 664 - 672
Date:	2011
Publisher:	GEORG THIEME VERLAG KG
Place of Publication:	STUTTGART
ISSN:	1438-8685
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language SALIVARY-GLANDS; CARCINOMA; NECK; SURGERY; THERAPY Multiple languages Otorhinolaryngology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/48582