Universität zu Köln

JayaNandanan, N., Gavis, Elizabeth R., Riechmann, Veit and Leptin, Maria (2011). A genetic in vivo system to detect asymmetrically distributed RNA. EMBO Rep., 12 (11). S. 1167 - 1175. LONDON: NATURE PUBLISHING GROUP. ISSN 1469-221X

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Abstract

Many RNAs show polarized or otherwise non-random subcellular distributions. To create a method for genome-wide genetic screens for RNAs with asymmetric subcellular distributions, we have combined methods for gene tagging and live imaging of messenger RNA (mRNA). A pilot screen in a highly polarized, differentiated cell in the Drosophila larva, the branched terminal cell of the tracheal system, demonstrates the feasibility of the method for identifying new asymmetrically localized mRNAs in vivo.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code JayaNandanan, N. UNSPECIFIED UNSPECIFIED UNSPECIFIED Gavis, Elizabeth R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Riechmann, Veit UNSPECIFIED UNSPECIFIED UNSPECIFIED Leptin, Maria UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-486199
DOI:	10.1038/embor.2011.178
Journal or Publication Title:	EMBO Rep.
Volume:	12
Number:	11
Page Range:	S. 1167 - 1175
Date:	2011
Publisher:	NATURE PUBLISHING GROUP
Place of Publication:	LONDON
ISSN:	1469-221X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language MESSENGER-RNAS; DROSOPHILA; LOCALIZATION; REVEALS; MORPHOGENESIS; EXPRESSION; PHENOTYPES; COMPONENT; GUIDANCE; ENCODES Multiple languages Biochemistry & Molecular Biology; Cell Biology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/48619