Universität zu Köln

Schuette, Jutta, Ye, Shute and Schmalz, Hans-Guenther ORCID: 0000-0003-0489-1827 (2011). Enantioselective Access to 3-Methylene-1H-indanol through Asymmetric Domino Allylstannylation-Heck Reaction. Synlett (18). S. 2725 - 2730. STUTTGART: GEORG THIEME VERLAG KG. ISSN 1437-2096

Full text not available from this repository.

Abstract

By screening various chiral P,P-ligands in the palladium-catalyzed reaction of ortho-iodobenzaldehyde with allyl tributylstannane, a suitable ligand (Taniaphos) was identified that affords 3-methylene-1-indanol with an enantioselectivity of 96% ee. This result indicates that a ligated palladium intermediate is involved in the chirogenic step of the catalytic cycle (intramolecular electrophilic activation of the aldehyde function by ortho-palladation).

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Schuette, Jutta UNSPECIFIED UNSPECIFIED UNSPECIFIED Ye, Shute UNSPECIFIED UNSPECIFIED UNSPECIFIED Schmalz, Hans-Guenther UNSPECIFIED orcid.org/0000-0003-0489-1827 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-486840
DOI:	10.1055/s-0031-1289539
Journal or Publication Title:	Synlett
Number:	18
Page Range:	S. 2725 - 2730
Date:	2011
Publisher:	GEORG THIEME VERLAG KG
Place of Publication:	STUTTGART
ISSN:	1437-2096
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language PHOSPHINE-PHOSPHITE-LIGANDS; BIDENTATE CHELATE LIGANDS; CIRCULAR-DICHROISM; ALLYLATION; REAGENTS; ALDEHYDES; HYDROGENATION; HYDROBORATION; ALKYLATION; TDDFT Multiple languages Chemistry, Organic Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/48684