Universität zu Köln

Bachmann, B. and Cursiefen, C. (2011). Late complications after chemical burns of the ocular surface. Surgical strategies for ocular surface reconstruction. Ophthalmologe, 108 (10). S. 929 - 939. NEW YORK: SPRINGER. ISSN 1433-0423

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Abstract

Severe chemical burns of the ocular surface frequently result in long-standing and ongoing disorders of the conjunctiva and the cornea including conjunctival scarring with shortening of the fornix, cicatricial entropion, complications caused by trichiasis and scarring or chronic ulceration of the cornea. Advanced destruction of limbal stem cells leads to limbal stem cell deficiency with conjunctivalization of the cornea. Surgical therapy aims at the correction of malpositioning of the lids, the reconstruction of the conjunctiva and the fornix utilizing applicable tissue grafts and the reestablishment of a stable, avascular and transparent corneal epithelium by e.g. transplantation of epithelial stem cells. Progressive corneal ulcerations unresponsive to medical therapy can be treated by amniotic membrane transplantation, corneal transplantation or by conjunctival covering depending on the extent of damaged tissue. The surgical therapy of patients after severe chemical burns of the ocular surface is generally performed in specialized centers and occasionally requires a multidisciplinary approach.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Bachmann, B. UNSPECIFIED UNSPECIFIED UNSPECIFIED Cursiefen, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-487821
DOI:	10.1007/s00347-010-2251-3
Journal or Publication Title:	Ophthalmologe
Volume:	108
Number:	10
Page Range:	S. 929 - 939
Date:	2011
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1433-0423
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language THERMAL EYE BURNS; AMNIOTIC MEMBRANE; CICATRICIAL ENTROPION; NASAL-MUCOSA; TRANSPLANTATION; CELLS; GRAFT Multiple languages Ophthalmology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/48782