Universität zu Köln

Hompes, Stephanie, Koehli, Alice, Nemat, Katja, Scherer, Kathrin, Lange, Lars, Rueff, Franziska, Rietschel, Ernst, Reese, Thomas, Szepfalusi, Zsolt ORCID: 0000-0003-4852-3102, Schwerk, Nicolaus, Beyer, Kirsten, Hawranek, Thomas, Niggemann, Bodo and Worm, Margitta ORCID: 0000-0002-3449-1245 (2011). Provoking allergens and treatment of anaphylaxis in children and adolescents - data from the anaphylaxis registry of German-speaking countries. Pediatr. Allergy Immunol., 22 (6). S. 568 - 575. MALDEN: WILEY-BLACKWELL. ISSN 0905-6157

Full text not available from this repository.

Abstract

Anaphylaxis is the most severe reaction of an IgE-mediated hypersensitivity. Data about affected patients may help to improve our knowledge of anaphylaxis and its medical care. We analysed data from the anaphylaxis registry of German speaking countries with regard to the provoking allergens and treatment modalities of anaphylaxis in children and adolescents. Inclusion criteria were severe systemic allergic reactions with concomitant pulmonary and/or cardiovascular symptoms. The data are collected by a password-controlled online-questionnaire. For this analysis, data of 197 reported anaphylactic reactions from children and adolescents registered between 2006 and 2009 were included. The data show that within the registered cases the most frequently affected organ systems for children and adolescents were the skin (89%) and the respiratory tract (87%) followed by symptoms of the cardiovascular system (47%) and the gastrointestinal tract (43%). The most frequent elicitors were food allergens accounting for 58% of cases, followed by insect venom (24%) and drugs (8%). The most frequent food allergens were peanuts followed by tree nuts and animal related food products. In 18% aggravating factors such as physical exercise were noted by the clinicians. 26% of the analysed patients had experienced more than one reaction. The data regarding the emergency treatment show that antihistamines (87%) and corticosteroids (85%) were often used but that adrenaline was rarely used (22% of the registered cases). Taken together these data show that the analysis of anaphylaxis by registration of affected individuals can provide data about provoking allergens and treatment measures but also suggest the impact of aggravating factors on anaphylactic reactions. The under-represented usage of adrenaline indicates the need of educational measures for patients and their physicians.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Hompes, Stephanie UNSPECIFIED UNSPECIFIED UNSPECIFIED Koehli, Alice UNSPECIFIED UNSPECIFIED UNSPECIFIED Nemat, Katja UNSPECIFIED UNSPECIFIED UNSPECIFIED Scherer, Kathrin UNSPECIFIED UNSPECIFIED UNSPECIFIED Lange, Lars UNSPECIFIED UNSPECIFIED UNSPECIFIED Rueff, Franziska UNSPECIFIED UNSPECIFIED UNSPECIFIED Rietschel, Ernst UNSPECIFIED UNSPECIFIED UNSPECIFIED Reese, Thomas UNSPECIFIED UNSPECIFIED UNSPECIFIED Szepfalusi, Zsolt UNSPECIFIED orcid.org/0000-0003-4852-3102 UNSPECIFIED Schwerk, Nicolaus UNSPECIFIED UNSPECIFIED UNSPECIFIED Beyer, Kirsten UNSPECIFIED UNSPECIFIED UNSPECIFIED Hawranek, Thomas UNSPECIFIED UNSPECIFIED UNSPECIFIED Niggemann, Bodo UNSPECIFIED UNSPECIFIED UNSPECIFIED Worm, Margitta UNSPECIFIED orcid.org/0000-0002-3449-1245 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-489589
DOI:	10.1111/j.1399-3038.2011.01154.x
Journal or Publication Title:	Pediatr. Allergy Immunol.
Volume:	22
Number:	6
Page Range:	S. 568 - 575
Date:	2011
Publisher:	WILEY-BLACKWELL
Place of Publication:	MALDEN
ISSN:	0905-6157
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language EXERCISE-INDUCED ANAPHYLAXIS; FOOD ALLERGY; MANAGEMENT; CHILDHOOD; ORGANIZATION; EPINEPHRINE; ANGIOEDEMA; URTICARIA; COMMUNITY Multiple languages Allergy; Immunology; Pediatrics Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/48958