Universität zu Köln

Karthaus, M., Rueping, M. J. G. T., Cornely, O. A., Steinbach, A., Groll, A. H., Lass-Floerl, C., Ostermann, H., Ruhnke, M. and Vehreschild, J. J. (2011). Current issues in the clinical management of invasive candida infections - the AGIHO, DMykG, OGMM and PEG web-based survey and expert consensus conference 2009. Mycoses, 54 (5). S. E546 - 11. HOBOKEN: WILEY. ISSN 1439-0507

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Abstract

The objectives of this study were to identify unsolved issues in the management of invasive candidiasis, identify controversies and achieve consensus. The German Speaking Mycological Society (Deutschsprachige Mykologische Gesellschaft, DMykG e.V.) asked other German infectious diseases (ID) and mycological societies to submit unsolved issues concerning the diagnosis and treatment of fungal infections. Based on these contributions, a digital web-based questionnaire of 12 questions on Candida infections was designed to be completed by experts of the participating societies. Controversial results were identified by a mathematical model and were discussed at a consensus conference during the 43rd Annual Meeting of the DMykG e.V. in Cologne, Germany. Forty-two individuals completed the questionnaire. Analysis showed a strong consensus on treatment indications, choice of antifungals for clinical situations, handling of central venous catheters, duration of treatment and role of susceptibility testing. Opinions diverged on: initial treatment of haemodynamically stable neutropenic and haemodynamically unstable non-neutropenic patients, step down to oral treatment and the differential role of the echinocandins. These questions were presented for discussion at the expert consensus conference. In three of four questions, consensus was achieved. A two-step approach - web-based survey plus classical panel discussion - allows to capture expeditiously the opinions of a large and diverse group of individuals, to identify controversial issues and to resolve them in a personal, interactive setting. Thus, expert consensus was achieved on nine of 12 important questions on how to treat invasive candidiasis.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Karthaus, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Rueping, M. J. G. T. UNSPECIFIED UNSPECIFIED UNSPECIFIED Cornely, O. A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Steinbach, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Groll, A. H. UNSPECIFIED UNSPECIFIED UNSPECIFIED Lass-Floerl, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Ostermann, H. UNSPECIFIED UNSPECIFIED UNSPECIFIED Ruhnke, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Vehreschild, J. J. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-489613
DOI:	10.1111/j.1439-0507.2010.01988.x
Journal or Publication Title:	Mycoses
Volume:	54
Number:	5
Page Range:	S. E546 - 11
Date:	2011
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1439-0507
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language AMPHOTERICIN-B; RISK-FACTORS; ANTIFUNGAL THERAPY; CARE; EPIDEMIOLOGY; FLUCONAZOLE; CASPOFUNGIN; MICAFUNGIN; MULTICENTER; GUIDELINES Multiple languages Dermatology; Mycology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/48961