Universität zu Köln

Kohler, Maxie, Thomas, Andreas ORCID: 0000-0003-1199-0743, Geyer, Hans, Petrou, Michael, Schaenzer, Wilhelm and Thevisa, Mario (2010). Confiscated Black Market Products and Nutritional Supplements with Non-Approved Ingredients Analyzed in the Cologne Doping Control Laboratory 2009. Drug Test. Anal., 2 (11-12). S. 533 - 538. HOBOKEN: WILEY-BLACKWELL. ISSN 1942-7611

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Abstract

Doping control laboratories are frequently confronted with new substances that may be misused by athletes. Besides new pharmaceuticals, where method development for their detection is dependant on the availability of the substance and corresponding administration studies, some professional and amateur athletes are using illicit 'black market' products, which either differ from known pharmaceuticals but cause similar effects or still are undergoing clinical trials and are therefore rarely available to doping control laboratories. In the Cologne Doping Control Laboratory, different confiscated products and legally obtained nutritional supplements were analyzed in 2009, and various findings were reported including GH-labelled injection vials without any pharmacologically active content; combinations of products indicating the attempt to mask growth hormone abuse; unpurified long-R-3-IGF-1; nutritional supplements containing the growth hormone releasing peptide-2 (GHRP-2); and ampoules containing the selective androgen receptor modulator Andarine (S-4). This review provides an overview on the substances that were analyzed in 2009. Ingredients relevant for doping control were identified by means of liquid chromatography and mass spectrometry methods. The awareness of new products on the black market and in nutritional supplements is of utmost importance for laboratories to develop detection methods accordingly and screen for new substances as early as possible. Copyright (C) 2010 John Wiley & Sons, Ltd.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Kohler, Maxie UNSPECIFIED UNSPECIFIED UNSPECIFIED Thomas, Andreas UNSPECIFIED orcid.org/0000-0003-1199-0743 UNSPECIFIED Geyer, Hans UNSPECIFIED UNSPECIFIED UNSPECIFIED Petrou, Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED Schaenzer, Wilhelm UNSPECIFIED UNSPECIFIED UNSPECIFIED Thevisa, Mario UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-493159
DOI:	10.1002/dta.186
Journal or Publication Title:	Drug Test. Anal.
Volume:	2
Number:	11-12
Page Range:	S. 533 - 538
Date:	2010
Publisher:	WILEY-BLACKWELL
Place of Publication:	HOBOKEN
ISSN:	1942-7611
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ANDROGEN RECEPTOR MODULATORS; TANDEM MASS-SPECTROMETRY; GROWTH-FACTOR-I; HORMONE-RELEASING PEPTIDE-2; TISSUE DISTRIBUTION; PLASMA-CLEARANCE; CONTROL PURPOSES; HUMAN URINE; IGF-I; GHRP-2 Multiple languages Biochemical Research Methods; Chemistry, Analytical; Pharmacology & Pharmacy Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/49315