Universität zu Köln

Bohnert, Michael, Anderson, Juerina, Rothschild, Markus A. and Boehm, Joachim (2010). Immunohistochemical expression of fibronectin in the lungs of fire victims proves intravital reaction in fatal burns. Int. J. Legal Med., 124 (6). S. 583 - 589. NEW YORK: SPRINGER. ISSN 0937-9827

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Abstract

Immunohistochemical studies about the presence of fibronectin in the lungs were performed in a group of 73 fire victims (63 cases of intravital and 10 cases of postmortem burn) as well as in an unselected control group of 55 individuals not exposed to fire before death. The cases of intravital burn showed a significantly stronger fibronectin expression than the control cases and the cases of postmortem burn. Fibronectin was mainly present in macrophages of the peribronchial lung parenchyma and, not associated with cells, in the matrix of peribronchial tissue. Our findings suggest that higher levels of fibronectin expression in the lung tissue of burn victims compared to fire-unrelated deaths may serve as an indicator of an early intravital inflammatory response to fire damage.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Bohnert, Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED Anderson, Juerina UNSPECIFIED UNSPECIFIED UNSPECIFIED Rothschild, Markus A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Boehm, Joachim UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-493427
DOI:	10.1007/s00414-010-0437-5
Journal or Publication Title:	Int. J. Legal Med.
Volume:	124
Number:	6
Page Range:	S. 583 - 589
Date:	2010
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	0937-9827
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language HUMAN SKIN WOUNDS; LOCALIZATION; MODULATION; VITALITY; INJURY Multiple languages Medicine, Legal Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/49342