Universität zu Köln

Wilmes, C., Heiligenhaus, A., Heinz, C., Velden, J., Wagner, N., Schneider, D. T. and Kalhoff, H. (2010). Sarcoidosis. A rare differential diagnosis of interstitial nephritis and uveitis. Mon.schr. Kinderheilkd., 158 (11). S. 1113 - 1117. NEW YORK: SPRINGER. ISSN 1433-0474

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Abstract

We report the case of a 13-year-old boy who presented with impaired exercise tolerance, loss of weight and fever. Laboratory data indicated systemic inflammation and renal failure suggestive of tubular dysfunction. A kidney biopsy showed epithelioid granulomatous tubulointerstitial nephritis. The boy developed granulomatous uveitis during follow-up. TINU syndrome (tubulointerstitial nephritis and uveitis) was diagnosed and sarcoidosis was considered to be the most probable cause. Treatment was started with prednisone and methotrexate and renal function completely recovered, whereas after 2 years of treatment the uveitis is still mildly active. Sarcoidosis is a rare disease of childhood; nevertheless it must be considered in the differential diagnosis of granulomatous uveitis and tubulointerstitial nephritis.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Wilmes, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Heiligenhaus, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Heinz, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Velden, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Wagner, N. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schneider, D. T. UNSPECIFIED UNSPECIFIED UNSPECIFIED Kalhoff, H. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-493773
DOI:	10.1007/s00112-010-2223-3
Journal or Publication Title:	Mon.schr. Kinderheilkd.
Volume:	158
Number:	11
Page Range:	S. 1113 - 1117
Date:	2010
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1433-0474
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language OF-THE-LITERATURE; TUBULOINTERSTITIAL NEPHRITIS; CHILDHOOD Multiple languages Pediatrics Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/49377