Universität zu Köln

Lenz, Maximilian, Oikonomidis, Stavros, Harland, Arne, Furnstahl, Philipp, Farshad, Mazda, Bredow, Jan, Eysel, Peer and Scheyerer, Max Joseph (2021). Scoliosis and Prognosis-a systematic review regarding patient-specific and radiological predictive factors for curve progression. Eur. Spine J., 30 (7). S. 1813 - 1823. NEW YORK: SPRINGER. ISSN 1432-0932

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Abstract

Introduction Idiopathic scoliosis, defined as a > 10 degrees curvature of the spine in the frontal plane, is one of the most common spinal deformities. Age, initial curve magnitude and other parameters define whether a scoliotic deformity will progress or not. Still, their interactions and amounts of individual contribution are not fully elaborated and were the aim of this systematic review. Methods A systematic literature search was conducted in the common databases using MESH terms, searching for predictive factors of curve progression in adolescent idiopathic scoliosis (adolescent idiopathic scoliosis OR ais OR idiopathic scoliosis) AND (predictive factors OR progression OR curve progression OR prediction OR prognosis). The identified and analysed factors of each study were rated to design a top five scale of the most relevant factors. Results Twenty-eight investigations with 8255 patients were identified by literature search. Patient-specific risk factors for curve progression from initial curve were age (at diagnosis < 13 years), family history, bone mineral status (< 110 mg/cm(3) in quantitative CT) and height velocity (7-8 cm/year, peak 11.6 +/- 1.4 years). Relevant radiological criteria indicating curve progression included skeletal maturity, marked by Risser stages (Risser < 1) or Sanders Maturity Scale (SMS < 5), the initial extent of the Cobb angle (> 25 degrees progression) and curve location (thoracic single or double curve). Discussion This systematic review summarised the current state of knowledge as the basis for creation of patient-specific algorithms regarding a risk calculation for a progressive scoliotic deformity. Curve magnitude is the most relevant predictive factor, followed by status of skeletal maturity and curve location.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Lenz, Maximilian UNSPECIFIED UNSPECIFIED UNSPECIFIED Oikonomidis, Stavros UNSPECIFIED UNSPECIFIED UNSPECIFIED Harland, Arne UNSPECIFIED UNSPECIFIED UNSPECIFIED Furnstahl, Philipp UNSPECIFIED UNSPECIFIED UNSPECIFIED Farshad, Mazda UNSPECIFIED UNSPECIFIED UNSPECIFIED Bredow, Jan UNSPECIFIED UNSPECIFIED UNSPECIFIED Eysel, Peer UNSPECIFIED UNSPECIFIED UNSPECIFIED Scheyerer, Max Joseph UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-570361
DOI:	10.1007/s00586-021-06817-0
Journal or Publication Title:	Eur. Spine J.
Volume:	30
Number:	7
Page Range:	S. 1813 - 1823
Date:	2021
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1432-0932
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ADOLESCENT IDIOPATHIC SCOLIOSIS; DEFORMITY PROGRESSION; RISK; VALIDATION Multiple languages Clinical Neurology; Orthopedics Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/57036